ID A0A084WP99_ANOSI Unreviewed; 638 AA.
AC A0A084WP99;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=AGAP012969-PA-like protein {ECO:0000313|EMBL:KFB52043.1};
GN ORFNames=ZHAS_00020227 {ECO:0000313|EMBL:KFB52043.1};
OS Anopheles sinensis (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=74873 {ECO:0000313|EMBL:KFB52043.1};
RN [1] {ECO:0000313|EMBL:KFB52043.1, ECO:0000313|Proteomes:UP000030765}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24438588; DOI=10.1186/1471-2164-15-42;
RA Zhou D., Zhang D., Ding G., Shi L., Hou Q., Ye Y., Xu Y., Zhou H.,
RA Xiong C., Li S., Yu J., Hong S., Yu X., Zou P., Chen C., Chang X., Wang W.,
RA Lv Y., Sun Y., Ma L., Shen B., Zhu C.;
RT "Genome sequence of Anopheles sinensis provides insight into genetics basis
RT of mosquito competence for malaria parasites.";
RL BMC Genomics 15:42-42(2014).
RN [2] {ECO:0000313|EnsemblMetazoa:ASIC020227-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (MAY-2020) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685}.
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DR EMBL; ATLV01024999; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KE525367; KFB52043.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A084WP99; -.
DR STRING; 74873.A0A084WP99; -.
DR EnsemblMetazoa; ASIC020227-RA; ASIC020227-PA; ASIC020227.
DR VEuPathDB; VectorBase:ASIC020227; -.
DR VEuPathDB; VectorBase:ASIS015095; -.
DR OMA; CLEEIWN; -.
DR Proteomes; UP000030765; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050906; P:detection of stimulus involved in sensory perception; IEA:UniProt.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR PANTHER; PTHR42643; IONOTROPIC RECEPTOR 20A-RELATED; 1.
DR PANTHER; PTHR42643:SF35; IONOTROPIC RECEPTOR 41A-RELATED; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030765};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 336..357
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 602..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 335..613
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00060"
SQ SEQUENCE 638 AA; 71826 MW; 0C822218BE2A1506 CRC64;
MDNVTQSIFR NDSSFDPRPL LGILLRSIVL KYFSQYFSFC TVGHDFLENV SIGKIQLTVD
EGSLEENLQR AIDNGCQAFL VDEPGIVPVL DLYIPVHDSS EQRSMDKRLI LLVTERNQQE
VLDRLVTHET LREIINVLIV VYDGDGRAAC CYTTAINYFG AHEPFNITLR QLPINWSDWE
RAMFFPDKSM DLDGYVLRMA TFNYLPFTGW WRVEPGLGNA FDSATGERSI LLDGTELLLV
VSFCERRNCT ILAVPGRGRD DEHEWGDIYP NGTGIGILGS VAERRTDIGL AAIYLWYKPY
SFTAYTASIS RSGVTVLVPK PRILPFWLTP FLSFSWPLWT AVMVTFVVGS GVAWAAGRVR
YRLLELISGQ EMPTSEQLPL SEVVLMMVGF FVAQSSPVRN DLWSCVFLFA SLLLAGFMVS
NLYSGGLASV MTVPQYEKSI DTVVDFAANG MWWYGPTPYC TEEIKNATQP HLKQLLTTFK
VATLEETQRL TRAGASAFII EQAQHGNFAP SNFLDRDTST AYQALRDDIY FQNCAALMTK
TNPLREALNA YILQVQQSGI LYHWGTTVAI RYLPTDVFRN IEQARLHRHV DGLVVTLEVD
HFLGAFCILG FGLLCATVTF VGELWGAEIV RRCTRCSK
//
