ID A0A085AFH8_9ENTR Unreviewed; 365 AA.
AC A0A085AFH8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Cobalt/zinc/cadmium efflux RND transporter membrane fusion protein {ECO:0000313|EMBL:KFC08973.1};
GN Name=cusB {ECO:0000313|EMBL:KFC08973.1};
GN ORFNames=GTGU_01164 {ECO:0000313|EMBL:KFC08973.1};
OS Trabulsiella guamensis ATCC 49490.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Trabulsiella.
OX NCBI_TaxID=1005994 {ECO:0000313|EMBL:KFC08973.1, ECO:0000313|Proteomes:UP000028630};
RN [1] {ECO:0000313|EMBL:KFC08973.1, ECO:0000313|Proteomes:UP000028630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49490 {ECO:0000313|EMBL:KFC08973.1,
RC ECO:0000313|Proteomes:UP000028630};
RA Plunkett G.III., Neeno-Eckwall E.C., Glasner J.D., Perna N.T.;
RT "ATOL: Assembling a taxonomically balanced genome-scale reconstruction of
RT the evolutionary history of the Enterobacteriaceae.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFC08973.1}.
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DR EMBL; JMTB01000044; KFC08973.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A085AFH8; -.
DR eggNOG; COG0845; Bacteria.
DR Proteomes; UP000028630; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0009636; P:response to toxic substance; IEA:UniProt.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 6.10.140.730; -; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR045800; HMBD.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR PANTHER; PTHR30097:SF15; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR Pfam; PF19335; HMBD; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
FT DOMAIN 1..23
FT /note="Heavy metal binding"
FT /evidence="ECO:0000259|Pfam:PF19335"
FT DOMAIN 58..267
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
SQ SEQUENCE 365 AA; 40353 MW; CDF08F0DAB2E8551 CRC64;
MKPDTKFDKP GKSPFMDMDL IPKYADEEGE KNDHGIRIDP TQVQNLGLKT EKVIKGQLNY
SQTIPANVSF NEYQFVIVQA RSDGFVEKVY PLTIGDKVKK GTPLIDITIP EWVEAQSEYL
LLSSTNGSAT QLKGVLERLR LAGMPENDIQ RLRSSRSIQT RFTITAPIDG VITAFDLRTG
MNISKDKVVA QIQGMDPVWI SAAVPESIAY LLKNTSQFEI SVPAYPDKTF NVEKWTLLPG
VDQTTRTLQV RLQVSNKDEQ LKPGMNAYLK VNTRSQDMLL IPSQAVIDTG SEQRVITVDK
DGRFVPKIIK VLHESQQQAG IGAGLSEGDS VVVSGLFLID SEANITGALE RMRHAENVAS
AHSGH
//
