ID A0A085AG93_9ENTR Unreviewed; 277 AA.
AC A0A085AG93;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Ferrous iron permease EfeU {ECO:0000256|ARBA:ARBA00021138};
DE AltName: Full=Fe(2+) ion permease EfeU {ECO:0000256|ARBA:ARBA00032812};
DE AltName: Full=Ferrous iron uptake protein {ECO:0000256|ARBA:ARBA00033458};
GN Name=efeU {ECO:0000313|EMBL:KFC09238.1};
GN ORFNames=GTGU_00963 {ECO:0000313|EMBL:KFC09238.1};
OS Trabulsiella guamensis ATCC 49490.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Trabulsiella.
OX NCBI_TaxID=1005994 {ECO:0000313|EMBL:KFC09238.1, ECO:0000313|Proteomes:UP000028630};
RN [1] {ECO:0000313|EMBL:KFC09238.1, ECO:0000313|Proteomes:UP000028630}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49490 {ECO:0000313|EMBL:KFC09238.1,
RC ECO:0000313|Proteomes:UP000028630};
RA Plunkett G.III., Neeno-Eckwall E.C., Glasner J.D., Perna N.T.;
RT "ATOL: Assembling a taxonomically balanced genome-scale reconstruction of
RT the evolutionary history of the Enterobacteriaceae.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Uptake of Fe(2+) ions across the membrane.
CC {ECO:0000256|ARBA:ARBA00003776}.
CC -!- SUBUNIT: Part of a ferrous iron transporter composed of EfeU, EfeO and
CC EfeB. {ECO:0000256|ARBA:ARBA00011401}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC
CC 9.A.10.1) family. {ECO:0000256|ARBA:ARBA00008333}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFC09238.1}.
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DR EMBL; JMTB01000042; KFC09238.1; -; Genomic_DNA.
DR RefSeq; WP_038154548.1; NZ_JMTB01000042.1.
DR AlphaFoldDB; A0A085AG93; -.
DR eggNOG; COG0672; Bacteria.
DR OrthoDB; 7260758at2; -.
DR Proteomes; UP000028630; Unassembled WGS sequence.
DR GO; GO:0033573; C:high-affinity iron permease complex; IEA:InterPro.
DR GO; GO:0005381; F:iron ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR005217; FTR1-like.
DR InterPro; IPR004923; FTR1/Fip1/EfeU.
DR InterPro; IPR036259; MFS_trans_sf.
DR NCBIfam; NF041756; EfeU; 1.
DR NCBIfam; TIGR00145; FTR1 family protein; 1.
DR PANTHER; PTHR31632; IRON TRANSPORTER FTH1; 1.
DR PANTHER; PTHR31632:SF2; PLASMA MEMBRANE IRON PERMEASE; 1.
DR Pfam; PF03239; FTR1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 38..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 183..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 277 AA; 30515 MW; 333A4AF3FAB9EEC0 CRC64;
MFVPFLIMLR EGLEAALIVS LIASYLKRTQ RGRWIGVMWI GVFLAAALCL GLGVFINETT
GEFPQKEQEL FEGLVALVAV VILTWMVFWM RKVSRNVKQQ LEQAVDNALQ RSNHHGWALI
LMVFFAVARE GLESVFFLLA AFQQDVGIWP PLGAVLGLAT AVVLGFLLYW GGIRLNLGAF
FKWTSLFILL VAAGLAAGAI RAFHEAGLWN NFQQVAFDFS NVLSTHSLTG TLMEGIFGYQ
EAPSVSEVAV YFIYLIPALV LFALPPRAGT TASRTAP
//
