ID A0A085BB67_9FLAO Unreviewed; 581 AA.
AC A0A085BB67;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Signal peptide peptidase SppA {ECO:0000313|EMBL:KFC19712.1};
GN ORFNames=IO90_10655 {ECO:0000313|EMBL:KFC19712.1};
OS Chryseobacterium sp. FH1.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=1233951 {ECO:0000313|EMBL:KFC19712.1, ECO:0000313|Proteomes:UP000028641};
RN [1] {ECO:0000313|EMBL:KFC19712.1, ECO:0000313|Proteomes:UP000028641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FH1 {ECO:0000313|EMBL:KFC19712.1,
RC ECO:0000313|Proteomes:UP000028641};
RA Pipes S.E., Stropko S.J.;
RT "Epilithonimonas sp. FH1 Genome.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S49 family.
CC {ECO:0000256|ARBA:ARBA00008683}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFC19712.1}.
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DR EMBL; JPLZ01000006; KFC19712.1; -; Genomic_DNA.
DR RefSeq; WP_034966139.1; NZ_JPLZ01000006.1.
DR AlphaFoldDB; A0A085BB67; -.
DR STRING; 1233951.IO90_10655; -.
DR eggNOG; COG0616; Bacteria.
DR OrthoDB; 9764363at2; -.
DR Proteomes; UP000028641; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006465; P:signal peptide processing; IEA:InterPro.
DR CDD; cd07018; S49_SppA_67K_type; 1.
DR CDD; cd07023; S49_Sppa_N_C; 1.
DR Gene3D; 6.20.330.10; -; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR004634; Pept_S49_pIV.
DR InterPro; IPR004635; Pept_S49_SppA.
DR InterPro; IPR002142; Peptidase_S49.
DR InterPro; IPR047217; S49_SppA_67K_type_N.
DR InterPro; IPR047272; S49_SppA_C.
DR NCBIfam; TIGR00705; SppA_67K; 1.
DR NCBIfam; TIGR00706; SppA_dom; 1.
DR PANTHER; PTHR33209; PROTEASE 4; 1.
DR PANTHER; PTHR33209:SF1; SERINE PROTEASE SPPA, CHLOROPLASTIC; 1.
DR Pfam; PF01343; Peptidase_S49; 2.
DR PIRSF; PIRSF001217; Protease_4_SppA; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000028641};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 121..265
FT /note="Peptidase S49"
FT /evidence="ECO:0000259|Pfam:PF01343"
FT DOMAIN 363..515
FT /note="Peptidase S49"
FT /evidence="ECO:0000259|Pfam:PF01343"
FT ACT_SITE 189
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001217-1"
FT ACT_SITE 380
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR001217-1"
SQ SEQUENCE 581 AA; 64427 MW; D6FF164CA6815B88 CRC64;
MKSFFKLVLA NLTAIFIVVA GFFAFFLFFI LISSVSETSD VKSESVLTLD LKTKIIDSPS
EDQEDFFAIN KEQKAVLLYD VLQAINKAKT DDKIKGISIE SDFISAGITQ LDDIRKALVD
FKKSGKFVYA YGNTVSQSAY YLGSVADKYY LNPSGGINLQ GLSAEVTFYK SFAEKYGIGI
QVIRHGKFKA AVEPFLKDEI SPENKEQLST LLNDIWNNTS TRIAASRNIP ASDFKMITDS
LYGYLPNLSL KYKLADQLIQ KSEYDNIIKK KLKIDADKKI NKISFAKYTN SIKDDGGKDK
IAVLYASGTI YNGKGYDAIY ADNFVKEIKK LQKDKNVKAV VFRINSPGGS ANASDEILFE
MQQLKRIKPV VVSFGDYAAS GGYYIAMGAD KIFSEPNTLT GSIGVFGVIP YFKELAAKNG
IRSDAVTTNA NSNMISAING LSPGAVTIMT RSVESTYQRF VHFVTQNRKK SFEQIDAVGG
GRIWSGVRAK EIGLVDELGN LQDAINYAAK SAKLKDYGVS TYPAKVSKFE QFFSPETDED
FSTRVIRNKI GKENFKIFQQ MTDPNAKATV MMETPFSIKL D
//
