ID A0A085EKQ1_9FLAO Unreviewed; 769 AA.
AC A0A085EKQ1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN ORFNames=FEM08_14640 {ECO:0000313|EMBL:KFC59796.1};
OS Flavobacterium gilvum.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1492737 {ECO:0000313|EMBL:KFC59796.1, ECO:0000313|Proteomes:UP000028636};
RN [1] {ECO:0000313|EMBL:KFC59796.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EM1308 {ECO:0000313|EMBL:KFC59796.1};
RA Shin S.-K., Yi H.;
RT "Genome Sequence of Flavobacterium sp. EM1308.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFC59796.1}.
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DR EMBL; JNCP01000037; KFC59796.1; -; Genomic_DNA.
DR RefSeq; WP_035636227.1; NZ_JNCP01000037.1.
DR AlphaFoldDB; A0A085EKQ1; -.
DR STRING; 1492737.EM308_12825; -.
DR KEGG; fgl:EM308_12825; -.
DR PATRIC; fig|1492737.3.peg.1452; -.
DR eggNOG; COG3525; Bacteria.
DR OrthoDB; 9763537at2; -.
DR Proteomes; UP000028636; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd06563; GH20_chitobiase-like; 1.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR026876; Fn3_assoc_repeat.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR015882; HEX_bac_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF13287; Fn3_assoc; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF02838; Glyco_hydro_20b; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000313|EMBL:KFC59796.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KFC59796.1};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..769
FT /note="beta-N-acetylhexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001788632"
FT DOMAIN 24..148
FT /note="Beta-hexosaminidase bacterial type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02838"
FT DOMAIN 151..504
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT DOMAIN 629..744
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|Pfam:PF00754"
FT ACT_SITE 335
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ SEQUENCE 769 AA; 86387 MW; 58DA88B880DA2BC7 CRC64;
MKRNVVLLLC LIVSGLSGAQ TSVHIIPQPV NLEMKSGNFI VDDKTSIKIS KKDKETERVV
HFFTEYVKKV TGFDLKANSK GNKIVFGIEK IEGIGEEGYL ISVNPNEILV KANTSKGLFY
GMQSLLQTLP FSRTNDLVQI PSMEIKDYPR FQWRGMMLDV SRHFFAPELV KEFIDLLAAY
KMNVFHWHLV DGAGWRLEIK KYPKLTQQAA WRIDDTAKPW NWAGIEFNSD RSKSTYGGYY
TQEQAKDIVA YAKERNITVV PEIEMPGHSE AAMAAYPELS CNSKVNFGVS GNFFASKGES
NYCAGNDQAF AFLEDILTEV MAIFPSKYIH IGGDEVDKTS WKNCAKCQAR MKAEQLKDEK
ELQSYFIRRI EKFVVSKNRK MIGWDEILEG GLAPEATVMS WQGEAGGIEA AKMGHDVIMT
PGSPCYFDHY QGDPETEPAA IGGFNTLKKV YNYEPIPTEL TQEEGKRVMG SQANLWTEYI
PTAEQAEYMI LPRMPALAEV LWSTKEQRNW EDFNKRLQPH LVGFDQKGLH YSKGNFKVDI
KPIVENGKLS IALETENSDG VIYYTTDGST PTTGSIKYEK PFDVNSFMTV KAIMVLNNKV
MNTKPAEQSF TFNKATGKTV AYTNPNSKYY PANGANTLTD GIKGTKNIGK QWHAFNGKDL
VATIDLGATT NVSSITLGCI QNWGQWVFLP QWVKFEVSND GINFKEIKTV NNSVSASEKE
MVIKDFAVKF TEEKAKVVRV TAKNLGLCPQ GHPGENQSAW LFVDEITVE
//
