ID A0A085G9T8_9ENTR Unreviewed; 807 AA.
AC A0A085G9T8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Potassium efflux system protein/small-conductance mechanosensitive channel {ECO:0000313|EMBL:KFC80483.1};
GN ORFNames=GBAG_2723 {ECO:0000313|EMBL:KFC80483.1};
OS Buttiauxella agrestis ATCC 33320.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Buttiauxella.
OX NCBI_TaxID=1006004 {ECO:0000313|EMBL:KFC80483.1, ECO:0000313|Proteomes:UP000028653};
RN [1] {ECO:0000313|EMBL:KFC80483.1, ECO:0000313|Proteomes:UP000028653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33320 {ECO:0000313|EMBL:KFC80483.1,
RC ECO:0000313|Proteomes:UP000028653};
RA Plunkett G.III., Neeno-Eckwall E.C., Glasner J.D., Perna N.T.;
RT "ATOL: Assembling a taxonomically balanced genome-scale reconstruction of
RT the evolutionary history of the Enterobacteriaceae.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFC80483.1}.
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DR EMBL; JMPI01000038; KFC80483.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A085G9T8; -.
DR STRING; 1006004.GBAG_2723; -.
DR eggNOG; COG3264; Bacteria.
DR Proteomes; UP000028653; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR022249; DUF3772.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049142; MS_channel_1st.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR PANTHER; PTHR30347:SF1; MINICONDUCTANCE MECHANOSENSITIVE CHANNEL MSCM; 1.
DR PANTHER; PTHR30347; POTASSIUM CHANNEL RELATED; 1.
DR Pfam; PF12607; DUF3772; 1.
DR Pfam; PF21088; MS_channel_1st; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028653};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..807
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001791016"
FT TRANSMEM 218..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 257..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..387
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 489..513
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 543..562
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 583..608
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 139..200
FT /note="DUF3772"
FT /evidence="ECO:0000259|Pfam:PF12607"
FT DOMAIN 589..630
FT /note="Mechanosensitive ion channel transmembrane helices
FT 2/3"
FT /evidence="ECO:0000259|Pfam:PF21088"
FT DOMAIN 632..697
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 709..787
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 807 AA; 87825 MW; 404ED45701702C7C CRC64;
MMQKMFKMPL LLAFLSCLIL TPFLSHADDS TGQTATEEPA KINASTALPA LQKRLDALKQ
RVSTAKTDKQ FTSLNDDSQK LASEADKLAV ALAPQLTQIQ AQLDVLGPPP APGTLAETPQ
VVSQRKQLNS SKTLLTTQIE QTKAISVGAQ NLSSQISGLR RDALKTQIAL NTGSILGEKF
WSPVIEPSDK DAVRFGDFGT QVGEAWDQAW SEEWRLGTGI YLLLALGIGL FGRRVLDSPM
NWVLPRWLPQ GRFRRSFLAC FTTLSTMLTL GISMQLLCYI FTRLPDTSAW INEFAEQLVE
LTYFSAVIAG LGIALLSNSH PSWRLPGIAD PLAKTLSSFP ILLATFIFIF GIIEQLNALV
GASIAATLFG NGLSALLVAL NCLVAPIRVN RIRRKMRADG EQTEARSTVA GLIHLVISLT
AFVILLALLI GYIPLARFVT FELLWIGLVV SSLYLLIHFV VDLCEAVFSP STQSGKILKS
TLSLNDRHLS LAATLFSALG KTSLLVMAAV ALLNGTFGTT TPMELLTKIA DMWGGKGLEG
MNIIPAHALN AVLCLVIGWY VLRSTRRWLD NDFLPKTNMD RGLRASLVTL FTNVGYVLII
MLTLSMLGIE WNKLAWIVSA LSVGIGFGLQ EIVKNFISGL ILLTERPVKV GDLVSISGVE
GDIRRINVRA TEIQLGDKST VIVPNSQLIS QNVRNATMGN AQGVATIALT FPLDIDPEQV
RNLLLEAYNL HESILENPKP SVSFKELGPT GIVLSVTGYV NSPRMVSSTR SDLLYEILKM
LRAAGVSLSQ TQTMVLEQPT SKVVTAE
//
