ID   A0A085GGX2_9ENTR        Unreviewed;       684 AA.
AC   A0A085GGX2;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 39.
DE   RecName: Full=DNA 3'-5' helicase {ECO:0000256|ARBA:ARBA00034808};
DE            EC=5.6.2.4 {ECO:0000256|ARBA:ARBA00034808};
GN   Name=helD {ECO:0000313|EMBL:KFC82967.1};
GN   ORFNames=GBAG_1340 {ECO:0000313|EMBL:KFC82967.1};
OS   Buttiauxella agrestis ATCC 33320.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Buttiauxella.
OX   NCBI_TaxID=1006004 {ECO:0000313|EMBL:KFC82967.1, ECO:0000313|Proteomes:UP000028653};
RN   [1] {ECO:0000313|EMBL:KFC82967.1, ECO:0000313|Proteomes:UP000028653}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33320 {ECO:0000313|EMBL:KFC82967.1,
RC   ECO:0000313|Proteomes:UP000028653};
RA   Plunkett G.III., Neeno-Eckwall E.C., Glasner J.D., Perna N.T.;
RT   "ATOL: Assembling a taxonomically balanced genome-scale reconstruction of
RT   the evolutionary history of the Enterobacteriaceae.";
RL   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=5.6.2.4;
CC         Evidence={ECO:0000256|ARBA:ARBA00034618};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFC82967.1}.
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DR   EMBL; JMPI01000022; KFC82967.1; -; Genomic_DNA.
DR   RefSeq; WP_034494362.1; NZ_JMPI01000022.1.
DR   AlphaFoldDB; A0A085GGX2; -.
DR   STRING; 1006004.GBAG_1340; -.
DR   eggNOG; COG0210; Bacteria.
DR   OrthoDB; 5298826at2; -.
DR   Proteomes; UP000028653; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR   CDD; cd17932; DEXQc_UvrD; 1.
DR   CDD; cd18807; SF1_C_UvrD; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR014017; DNA_helicase_UvrD-like_C.
DR   InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR   InterPro; IPR022161; Helicase_IV_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014016; UvrD-like_ATP-bd.
DR   PANTHER; PTHR11070:SF63; DNA HELICASE IV; 1.
DR   PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR   Pfam; PF12462; Helicase_IV_N; 1.
DR   Pfam; PF00580; UvrD-helicase; 1.
DR   Pfam; PF13361; UvrD_C; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW   ProRule:PRU00560};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW   ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000028653}.
FT   DOMAIN          195..505
FT                   /note="UvrD-like helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51198"
FT   BINDING         216..223
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ   SEQUENCE   684 AA;  78382 MW;  F6096AFCD64F3768 CRC64;
     MELKATSLGK HLAQHPYNRV KLLAAGVEVK GERHEYLIPF NQLIAINCKR GLVWGELEFV
     LPDDKVVRLH GTEWNETQRF YHHLDQLWQS WSVEMSEVAA QVLQQQYAEI TRRIQQEKWF
     KRSDMQALQQ NVRVAFSALP LPQARLEDFD NCRELWMHCK AWLEQGETRR HQRNTAYTNH
     MLEKHADFFQ KIESSPLNHS QARAVVNGED SLLVLAGAGS GKTSVLVARA GWLLQRGEAS
     EDQILLLAFG RKAAQEMDER IAERLHTDAI SARTFHALAL HIIQQGSKKA PRVSELESDT
     NARHQLLIES WQQQCREKKA QAKGWREWLR DELQWDVPEG EYWKDERLAK RLASRLDRWL
     GLMRMHGGSQ ADMIASAPED IRDLFAKRVK LMAPLLKTWK TALKAEEAVD FSGLIHQAIN
     VLEKGRFISP WKHILVDEFQ DISPQRAALL AALRKQNSHT SLYAVGDDWQ AIYRFSGAEM
     SLTTAFAQNF GDADQCALDT TYRFNDRIGE IANRFVQQNP HQLAKPLNSL SKGDKKAVTL
     LADDQLEALL DKMSGYVQPQ ERILVLARYH HLRPAILEKA ATRWPKLAVD FMTIHASKGQ
     QADYVVVLGL QQGKDGFPAV ARESVMEEAL LPQPEDYPDA EERRLLYVAM TRARHRVWLL
     FNKHEPSSFV DILKQLGVPA ANRP
//