ID A0A085GH97_9ENTR Unreviewed; 335 AA.
AC A0A085GH97;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=DNA polymerase III subunit delta' {ECO:0000256|ARBA:ARBA00014363};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN Name=holB {ECO:0000313|EMBL:KFC83092.1};
GN ORFNames=GBAG_1468 {ECO:0000313|EMBL:KFC83092.1};
OS Buttiauxella agrestis ATCC 33320.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Buttiauxella.
OX NCBI_TaxID=1006004 {ECO:0000313|EMBL:KFC83092.1, ECO:0000313|Proteomes:UP000028653};
RN [1] {ECO:0000313|EMBL:KFC83092.1, ECO:0000313|Proteomes:UP000028653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33320 {ECO:0000313|EMBL:KFC83092.1,
RC ECO:0000313|Proteomes:UP000028653};
RA Plunkett G.III., Neeno-Eckwall E.C., Glasner J.D., Perna N.T.;
RT "ATOL: Assembling a taxonomically balanced genome-scale reconstruction of
RT the evolutionary history of the Enterobacteriaceae.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFC83092.1}.
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DR EMBL; JMPI01000022; KFC83092.1; -; Genomic_DNA.
DR RefSeq; WP_034494550.1; NZ_JMPI01000022.1.
DR AlphaFoldDB; A0A085GH97; -.
DR STRING; 1006004.GBAG_1468; -.
DR eggNOG; COG0470; Bacteria.
DR OrthoDB; 9811073at2; -.
DR Proteomes; UP000028653; Unassembled WGS sequence.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR004622; DNA_pol_HolB.
DR InterPro; IPR015199; DNA_pol_III_delta_C.
DR InterPro; IPR048731; HolB_lid-gammaproteobact.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00678; holB; 1.
DR PANTHER; PTHR11669:SF8; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR11669; REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT; 1.
DR Pfam; PF13177; DNA_pol3_delta2; 1.
DR Pfam; PF09115; DNApol3-delta_C; 1.
DR Pfam; PF21500; HolB_lid; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW ECO:0000313|EMBL:KFC83092.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000028653};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KFC83092.1}.
FT DOMAIN 167..206
FT /note="DNA polymerase III subunit delta' AAA+ ATPase lid"
FT /evidence="ECO:0000259|Pfam:PF21500"
FT DOMAIN 208..321
FT /note="DNA polymerase III delta subunit C-terminal"
FT /evidence="ECO:0000259|Pfam:PF09115"
SQ SEQUENCE 335 AA; 37211 MW; A625E1F86B677666 CRC64;
MKWYPWLRAP FEQILSQYQS GRGHHALLLH SLSGMGDDAL IYALTRWIMC QTPQGNKSCG
QCRSCQLMQA GTHPDSYVIA PEKGKSSLGI DAIREMTEKL YSHAQQGGAK VVWLEDAGLL
TEAAANALLK TLEEPPAKTW FFLGCREPAR LPATLRSRCL YWYLTPPDET FALAWLAREI
TLDSAQLRAA LRLNSGAPAG ALALLQPESW KHRQALCDKL SECCATKNML ALLPALNSDD
AAVRLHWLSS LLVDALKWQQ GATAWLTNDD QQALVANLAN SATPAMLQAI LHNWFNCRES
LLSVVGVNRE LLLTEQLLTW ERIMQPGAVL PTFHL
//
