ID A0A085JI11_9GAMM Unreviewed; 395 AA.
AC A0A085JI11;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Nucleoside permease {ECO:0000256|RuleBase:RU362018};
GN Name=nupC {ECO:0000313|EMBL:KFD20107.1};
GN ORFNames=GTPT_1562 {ECO:0000313|EMBL:KFD20107.1};
OS Tatumella ptyseos ATCC 33301.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Tatumella.
OX NCBI_TaxID=1005995 {ECO:0000313|EMBL:KFD20107.1, ECO:0000313|Proteomes:UP000028602};
RN [1] {ECO:0000313|EMBL:KFD20107.1, ECO:0000313|Proteomes:UP000028602}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 33301 {ECO:0000313|EMBL:KFD20107.1,
RC ECO:0000313|Proteomes:UP000028602};
RA Plunkett G.III., Neeno-Eckwall E.C., Glasner J.D., Perna N.T.;
RT "ATOL: Assembling a taxonomically balanced genome-scale reconstruction of
RT the evolutionary history of the Enterobacteriaceae.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the concentrative nucleoside transporter (CNT)
CC (TC 2.A.41) family. {ECO:0000256|ARBA:ARBA00009033,
CC ECO:0000256|RuleBase:RU362018}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFD20107.1}.
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DR EMBL; JMPR01000027; KFD20107.1; -; Genomic_DNA.
DR RefSeq; WP_025903566.1; NZ_JMPR01000027.1.
DR AlphaFoldDB; A0A085JI11; -.
DR eggNOG; COG1972; Bacteria.
DR OrthoDB; 9766455at2; -.
DR Proteomes; UP000028602; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR008276; C_nuclsd_transpt.
DR InterPro; IPR018270; C_nuclsd_transpt_met_bac.
DR InterPro; IPR011657; CNT_C_dom.
DR InterPro; IPR002668; CNT_N_dom.
DR InterPro; IPR011642; Gate_dom.
DR NCBIfam; TIGR00804; nupC; 1.
DR PANTHER; PTHR10590:SF21; NUCLEOSIDE PERMEASE NUPC; 1.
DR PANTHER; PTHR10590; SODIUM/NUCLEOSIDE COTRANSPORTER; 1.
DR Pfam; PF07670; Gate; 1.
DR Pfam; PF07662; Nucleos_tra2_C; 1.
DR Pfam; PF01773; Nucleos_tra2_N; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362018};
KW Reference proteome {ECO:0000313|Proteomes:UP000028602};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362018};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362018}; Transport {ECO:0000256|RuleBase:RU362018}.
FT TRANSMEM 6..22
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 29..48
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 87..108
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 167..187
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 193..212
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 241..263
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 269..293
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 335..355
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 375..394
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT DOMAIN 9..82
FT /note="Concentrative nucleoside transporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01773"
FT DOMAIN 91..191
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT DOMAIN 193..391
FT /note="Concentrative nucleoside transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07662"
SQ SEQUENCE 395 AA; 43057 MW; 8FAF7D546757DADD CRC64;
MAHIFHFILA MVVVAALALL ASKNRKQIRI RYVIQLLVIE VLLAWFFLNS EAGLGFVRAF
AGFFDTLLKY AAEGTNFVFG GMNDKGMAFF FLNVLCPIVF ISALIGILQH FRVLPLVIRA
IGTVLSKING MGKLESFNAV SSLILGQSEN FIAYKDILGK MSHNRMYTMA ATAMSTVSMS
IVGAYMTMLQ PKYVVAALIL NMFSTFIVLS IINPYKVEQE DDLQLKNTHE GQSFFEMLGE
YIIAGFRVAI IVAAMLIGFI ALISAINALF TTIFGISFQG VLGYLFYPFA WIIGVPADEA
LKVGSVMATK LVSNEFVAMM DLQKMASQLT PRSEGILSVF LVSFANFSSI GIVAGAIRGL
NEEQGNIVSR FGLKLLYGST LVSLLSAAVA GLVLA
//
