ID A0A085LRE8_9BILA Unreviewed; 387 AA.
AC A0A085LRE8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Protein-tyrosine phosphatase {ECO:0000313|EMBL:KHJ41318.1};
GN ORFNames=D918_08649 {ECO:0000313|EMBL:KHJ41318.1}, M513_11588
GN {ECO:0000313|EMBL:KFD47544.1}, M514_11588
GN {ECO:0000313|EMBL:KFD60253.1};
OS Trichuris suis (pig whipworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichuridae; Trichuris.
OX NCBI_TaxID=68888 {ECO:0000313|EMBL:KFD47544.1, ECO:0000313|Proteomes:UP000030764};
RN [1] {ECO:0000313|EMBL:KFD47544.1, ECO:0000313|Proteomes:UP000030764}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DCEP-RM93F {ECO:0000313|EMBL:KFD60253.1}, and DCEP-RM93M
RC {ECO:0000313|EMBL:KFD47544.1};
RX PubMed=24929829; DOI=10.1038/ng.3012;
RA Jex A.R., Nejsum P., Schwarz E.M., Hu L., Young N.D., Hall R.S.,
RA Korhonen P.K., Liao S., Thamsborg S., Xia J., Xu P., Wang S.,
RA Scheerlinck J.P., Hofmann A., Sternberg P.W., Wang J., Gasser R.B.;
RT "Genome and transcriptome of the porcine whipworm Trichuris suis.";
RL Nat. Genet. 46:701-706(2014).
RN [2] {ECO:0000313|EMBL:KHJ41318.1, ECO:0000313|Proteomes:UP000053709}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mitreva M.;
RT "Draft genome of Trichuris suis.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL363323; KFD47544.1; -; Genomic_DNA.
DR EMBL; KL367682; KFD60253.1; -; Genomic_DNA.
DR EMBL; KN538419; KHJ41318.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A085LRE8; -.
DR Proteomes; UP000030758; Unassembled WGS sequence.
DR Proteomes; UP000030764; Unassembled WGS sequence.
DR Proteomes; UP000053709; Unassembled WGS sequence.
DR GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd00047; PTPc; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR000242; PTP_cat.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR003595; Tyr_Pase_cat.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR19134:SF544; LD27988P; 1.
DR PANTHER; PTHR19134; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE; 1.
DR Pfam; PF00102; Y_phosphatase; 1.
DR PRINTS; PR00700; PRTYPHPHTASE.
DR SMART; SM00194; PTPc; 1.
DR SMART; SM00404; PTPc_motif; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
DR PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053709}.
FT DOMAIN 59..296
FT /note="Tyrosine-protein phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS50055"
FT DOMAIN 209..287
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 329..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 387 AA; 43875 MW; 61D40C320192BD53 CRC64;
MIPKGKPTIA SDSKAAEWVR HIAANPTGTL KNIACEFTNK LPQRPPMKEA MEFYKNLPMK
RNRYGDIPCL DRTRVKLAEP RDGNDYIHAN VVVMPQHKCR YILTQAPLPD TIQDFWAMVW
QENVSLIVCL TKILERGKTK TQEYWPTCCG KQYHQRYGFV HVRNVGIRNA KQYSISILEI
ANERTMEKRK LTHYLYLDWP DHRVPICTHN FLQLAEFMDS QLVQYSGKDP MCVIVHCSAG
VGRSGTLVAL QALMAVVNAG EEPNVLATVT DVRLQRAMSV QGPEQYLFLY YALAVHILLN
VSISEEDRKE LLQKIIPLRE CSTKSRCGKM PELKKQSAKL SRLVGTAGNS KQQENPAGEH
VRRQKSSSVG PKMAAGQKRQ SGVRRSA
//
