ID A0A085LT24_9BILA Unreviewed; 656 AA.
AC A0A085LT24;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=BTB domain-containing protein {ECO:0000259|SMART:SM00225};
GN ORFNames=M513_11001 {ECO:0000313|EMBL:KFD48120.1}, M514_11001
GN {ECO:0000313|EMBL:KFD61810.1};
OS Trichuris suis (pig whipworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichuridae; Trichuris.
OX NCBI_TaxID=68888 {ECO:0000313|EMBL:KFD48120.1, ECO:0000313|Proteomes:UP000030764};
RN [1] {ECO:0000313|EMBL:KFD48120.1, ECO:0000313|Proteomes:UP000030764}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DCEP-RM93F {ECO:0000313|EMBL:KFD61810.1}, and DCEP-RM93M
RC {ECO:0000313|EMBL:KFD48120.1};
RX PubMed=24929829; DOI=10.1038/ng.3012;
RA Jex A.R., Nejsum P., Schwarz E.M., Hu L., Young N.D., Hall R.S.,
RA Korhonen P.K., Liao S., Thamsborg S., Xia J., Xu P., Wang S.,
RA Scheerlinck J.P., Hofmann A., Sternberg P.W., Wang J., Gasser R.B.;
RT "Genome and transcriptome of the porcine whipworm Trichuris suis.";
RL Nat. Genet. 46:701-706(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KL363303; KFD48120.1; -; Genomic_DNA.
DR EMBL; KL367610; KFD61810.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A085LT24; -.
DR Proteomes; UP000030758; Unassembled WGS sequence.
DR Proteomes; UP000030764; Unassembled WGS sequence.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003968; K_chnl_volt-dep_Kv.
DR InterPro; IPR003975; K_chnl_volt-dep_Kv4.
DR InterPro; IPR021645; Shal-type_N.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF105; POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAL; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF11601; Shal-type; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01491; KVCHANNEL.
DR PRINTS; PR01497; SHALCHANNEL.
DR SMART; SM00225; BTB; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 188..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..352
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..380
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..143
FT /note="BTB"
FT /evidence="ECO:0000259|SMART:SM00225"
FT REGION 560..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..585
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 602..627
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 634..649
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 656 AA; 74395 MW; 92D7CF8196659877 CRC64;
MDSMNAWLPF ARAAAIGWVP LSRRPMPISP LSMISQERLK APDERLTINV SGQRFETWKI
TLERYPETLL GGKEKEFFYD EQAKEYFFDR DPNLFRYILS FYRTGKLHFP KNECMTAFED
ELAFFGIITE MISDCCYEDY KDKKRENQER LMDEHSDTDA KAAVPLNMTV REKMWRAFEN
PHSSTPALAF YYVTGFFIAV SVLSNVVETV SCKTILSPEG IVLQSITCGD LYDVQFFVVD
TACVIIFTIE YLLRLYAAPN RYKFVRSVMS IIDVVAILPY YVGLGLQGNK DVSGAFVTLR
VFRVFRIFKF SRHSQGLRIL GYTLKSCASE LGFLVFSLAM AIVIFATIMY YCEKKMVGTT
FTSIPAAFWY TIVTMTTLGY GDMVPSTMVG KVIGGVCSLS GVLVIALPVP VIVSNFSRIY
HQNQRADKRR AQKKLRMARI QIVKRASGQA IAHKRRTNEA RMHEFELGRL APEDLSKEDI
CGLQYQYLLK CLESVTERKV ENIEPVTQQR DTSIAFCSVS SSPFPLSHNS SLDLNDKTPT
EERTLSACCR WLAQHCASAR RSPGDQATAK GSKKTSKKTR EKDYGSEGPS ITPASGDHIT
LIPMDTEDDR RATRKKCKDE QTIQSTTPRR HRHSASIKLA DEEDYSSDRS ADTSVL
//
