ID   A0A085LZI2_9BILA        Unreviewed;       597 AA.
AC   A0A085LZI2;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   13-SEP-2023, entry version 29.
DE   RecName: Full=BMP-binding endothelial regulator protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=M513_08760 {ECO:0000313|EMBL:KFD50378.1}, M514_08760
GN   {ECO:0000313|EMBL:KFD65403.1};
OS   Trichuris suis (pig whipworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichuridae; Trichuris.
OX   NCBI_TaxID=68888 {ECO:0000313|EMBL:KFD50378.1, ECO:0000313|Proteomes:UP000030764};
RN   [1] {ECO:0000313|EMBL:KFD50378.1, ECO:0000313|Proteomes:UP000030764}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DCEP-RM93F {ECO:0000313|EMBL:KFD65403.1}, and DCEP-RM93M
RC   {ECO:0000313|EMBL:KFD50378.1};
RX   PubMed=24929829; DOI=10.1038/ng.3012;
RA   Jex A.R., Nejsum P., Schwarz E.M., Hu L., Young N.D., Hall R.S.,
RA   Korhonen P.K., Liao S., Thamsborg S., Xia J., Xu P., Wang S.,
RA   Scheerlinck J.P., Hofmann A., Sternberg P.W., Wang J., Gasser R.B.;
RT   "Genome and transcriptome of the porcine whipworm Trichuris suis.";
RL   Nat. Genet. 46:701-706(2014).
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DR   EMBL; KL363254; KFD50378.1; -; Genomic_DNA.
DR   EMBL; KL367539; KFD65403.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A085LZI2; -.
DR   Proteomes; UP000030758; Unassembled WGS sequence.
DR   Proteomes; UP000030764; Unassembled WGS sequence.
DR   Gene3D; 6.20.200.20; -; 3.
DR   InterPro; IPR001007; VWF_dom.
DR   InterPro; IPR001846; VWF_type-D.
DR   PANTHER; PTHR46698; CROSSVEINLESS 2; 1.
DR   PANTHER; PTHR46698:SF4; CROSSVEINLESS 2; 1.
DR   Pfam; PF00093; VWC; 2.
DR   Pfam; PF00094; VWD; 1.
DR   SMART; SM00214; VWC; 4.
DR   SMART; SM00215; VWC_out; 1.
DR   SMART; SM00216; VWD; 1.
DR   SUPFAM; SSF57603; FnI-like domain; 4.
DR   PROSITE; PS01208; VWFC_1; 1.
DR   PROSITE; PS50184; VWFC_2; 3.
DR   PROSITE; PS51233; VWFD; 1.
PE   4: Predicted;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..597
FT                   /note="BMP-binding endothelial regulator protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5010405198"
FT   DOMAIN          89..147
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          211..270
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          275..336
FT                   /note="VWFC"
FT                   /evidence="ECO:0000259|PROSITE:PS50184"
FT   DOMAIN          340..521
FT                   /note="VWFD"
FT                   /evidence="ECO:0000259|PROSITE:PS51233"
SQ   SEQUENCE   597 AA;  67481 MW;  158D4042681EF622 CRC64;
     MLQAVCLYML LFAGERLGGA QSVAVLKSYP YACDREGDLL YIKGITSDPC ITCICKDGTA
     HCITKKCPSA QRCPVVVRNQ SGSCCKECKN CVYLDVTYKS GEQWMSTQDS CRRLTCKAGV
     VTSARIQCIV PCSNAKRVVG LCCPVCPQAQ NFTANLPSDP CVQCQCNDHW CHCFQTACPV
     LNCPPSEQYV PDTACCPECR KSREDLSLPM RICFFQNKVY QLEQSFRPDP CTLCLCQETG
     VLCRRFVCPQ IACLKHRLHF TAGLCCPLCR GYDFLPCSYH GSLYRDGQTW KKDSCTKCKC
     SNGKVHCVRQ RCAGDKKCPR DYSSKPVPGQ CCSVCVEKEA TCLVSNDLHY KTFDGREYNF
     RGSCRYILAQ ECLPNSVRPH RPNFLIVVRN EPRNNGTSYW TRHVSIRLQN KIRISLLPAK
     KVSLNGEKVS LPYVELGVFS VMYDKTSRVL VRLNAGPKVV WDGNGQVEVT VTSQYKGRLC
     GLCGNYNNNA KDDFFTKSGT LLKSAQRFGR SWRVGSWRAC KTEQDRRFHL RRRGKDKQSK
     RKNSWQKSRL TWILLNDLTD SETVAFHGVA QNQKHMYTKG QLVAGKLPVL KWQQPET
//