ID   A0A085NFP2_9BILA        Unreviewed;      1022 AA.
AC   A0A085NFP2;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   22-FEB-2023, entry version 29.
DE   RecName: Full=Dynamin-like 120 kDa protein, mitochondrial {ECO:0000256|ARBA:ARBA00018307};
DE            EC=3.6.5.5 {ECO:0000256|ARBA:ARBA00011980};
DE   Flags: Fragment;
GN   ORFNames=M514_03078 {ECO:0000313|EMBL:KFD68288.1};
OS   Trichuris suis (pig whipworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Trichinellida; Trichuridae; Trichuris.
OX   NCBI_TaxID=68888 {ECO:0000313|EMBL:KFD68288.1};
RN   [1] {ECO:0000313|EMBL:KFD68288.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DCEP-RM93F {ECO:0000313|EMBL:KFD68288.1};
RX   PubMed=24929829; DOI=10.1038/ng.3012;
RA   Jex A.R., Nejsum P., Schwarz E.M., Hu L., Young N.D., Hall R.S.,
RA   Korhonen P.K., Liao S., Thamsborg S., Xia J., Xu P., Wang S.,
RA   Scheerlinck J.P., Hofmann A., Sternberg P.W., Wang J., Gasser R.B.;
RT   "Genome and transcriptome of the porcine whipworm Trichuris suis.";
RL   Nat. Genet. 46:701-706(2014).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; EC=3.6.5.5;
CC         Evidence={ECO:0000256|ARBA:ARBA00001837};
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004167}. Mitochondrion
CC       inner membrane {ECO:0000256|ARBA:ARBA00004434}; Single-pass membrane
CC       protein {ECO:0000256|ARBA:ARBA00004434}. Mitochondrion membrane
CC       {ECO:0000256|ARBA:ARBA00004325}.
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DR   EMBL; KL367506; KFD68288.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A085NFP2; -.
DR   Proteomes; UP000030758; Unassembled WGS sequence.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   CDD; cd08771; DLP_1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR022812; Dynamin.
DR   InterPro; IPR001401; Dynamin_GTPase.
DR   InterPro; IPR045063; Dynamin_N.
DR   InterPro; IPR030381; G_DYNAMIN_dom.
DR   InterPro; IPR045817; OPA1_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11566; DYNAMIN; 1.
DR   PANTHER; PTHR11566:SF67; DYNAMIN-LIKE 120 KDA PROTEIN, MITOCHONDRIAL; 1.
DR   Pfam; PF00350; Dynamin_N; 1.
DR   Pfam; PF19434; OPA1_C; 1.
DR   PRINTS; PR00195; DYNAMIN.
DR   SMART; SM00053; DYNc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51718; G_DYNAMIN_2; 1.
PE   4: Predicted;
KW   Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW   Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW   Transit peptide {ECO:0000256|ARBA:ARBA00022946};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT   DOMAIN          336..610
FT                   /note="Dynamin-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51718"
FT   COILED          277..304
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          942..974
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFD68288.1"
SQ   SEQUENCE   1022 AA;  116523 MW;  DD1EA5270A3E76B6 CRC64;
     LPPFVEFISW FKQHLKDFID YEEICVPLVA LLSNAKALLF KLLSSDDMWR SRLSSIAWRI
     SRKQHESRRH FSAFGRCYKQ SFIIKFSSSC KLLTPPLPFT AAVYGKRNVS ILVNLGRSLL
     RVRYIVIGSL VGGGITVSQT VQSWKDKMPD FGWFTDHWPD ADSMNKYIDY VKGIPDVVQQ
     RGRHFNERLH SNGSVTINYL RDWLGSFNGS VLTSFSKGLG PVSYNVISSH SLLGMALYSG
     MPEWEELESS YLLPIAEESS QPIGNPVVNK DDSLDLQLKF QRQMEKLEKE NAELRHLLTL
     NNKTTDRPRR SRQSLIEMYS EVLDILADYD ASYKTQDCLP RVIVVGDQSS GKTSVLEMIA
     QARIFPRGSG EMMTRAPVKV TLSEGPYHVA KFKDSEREFD LTKESELAEL RHEIELRMRN
     SVTDGKTVSK EVIALAVQGP SLPRMVLIDL PGVISTVTSE MAVGTKNDIL DICRCHMENP
     NAIILCIQDG SVDAERSNVT DLVSSLDPQG KRTILVLTKV DLAEENLINP NRVKKILDGK
     LFPMKAIGYF AVVAGKGNQG DSIEAIKEYE EEFFANSKLF RALESSQLTT RNMSLAVSDR
     FWTMVKESVE EQADSFKAKR FNLETEWRNT FPKKRELDRD ELFEKARNEL LDEINALEEI
     ASKDWETALR EKIWKRMSSH VFDKLYFPAA VEESIGAFTT SIDIKLKRWV DNALPAICVE
     AAWDTLREKL TDIVAQDASK TDHVPLFEPL KNAIIEQAFA AHEWDPKACH YLRVIQSNAI
     EDHNVPDKAS WEMASQFMES AVKEQLTNVE QTFREMLGPS WSEKWLRWAS AKEAQVQRSL
     MVEELKPLLR ARKASCTLSN NANRKPFLEP EEVALACRNI EVKGGKASSE ELRDVWHHLF
     HKNFLHNALS SARECKNLFV HYQNGFLEAA DCASIVVFWR IHRMLNATVN ALRQQLVNKE
     ARRLEAEIKR VIVEWSQNAD VKKKFIVGRQ VELAEQLKQV RLIQAKLDEF ISALNSSNTL
     ET
//