ID A0A085NMP5_9BILA Unreviewed; 1508 AA.
AC A0A085NMP5;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=HMG box domain-containing protein {ECO:0000259|PROSITE:PS50118};
GN ORFNames=M514_06027 {ECO:0000313|EMBL:KFD70741.1};
OS Trichuris suis (pig whipworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichuridae; Trichuris.
OX NCBI_TaxID=68888 {ECO:0000313|EMBL:KFD70741.1};
RN [1] {ECO:0000313|EMBL:KFD70741.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DCEP-RM93F {ECO:0000313|EMBL:KFD70741.1};
RX PubMed=24929829; DOI=10.1038/ng.3012;
RA Jex A.R., Nejsum P., Schwarz E.M., Hu L., Young N.D., Hall R.S.,
RA Korhonen P.K., Liao S., Thamsborg S., Xia J., Xu P., Wang S.,
RA Scheerlinck J.P., Hofmann A., Sternberg P.W., Wang J., Gasser R.B.;
RT "Genome and transcriptome of the porcine whipworm Trichuris suis.";
RL Nat. Genet. 46:701-706(2014).
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DR EMBL; KL367486; KFD70741.1; -; Genomic_DNA.
DR Proteomes; UP000030758; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd21990; HMG-box_CIC-like; 1.
DR Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR InterPro; IPR032147; DUF4819.
DR InterPro; IPR009071; HMG_box_dom.
DR InterPro; IPR036910; HMG_box_dom_sf.
DR PANTHER; PTHR13059; HMG-BOX TRANSCRIPTION FACTOR BBX; 1.
DR PANTHER; PTHR13059:SF16; TRANSCRIPTION FACTOR CAPICUA-RELATED; 1.
DR Pfam; PF16090; DUF4819; 1.
DR Pfam; PF00505; HMG_box; 1.
DR SMART; SM00398; HMG; 1.
DR SUPFAM; SSF47095; HMG-box; 1.
DR PROSITE; PS50118; HMG_BOX_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00267};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00267}; Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 689..757
FT /note="HMG box"
FT /evidence="ECO:0000259|PROSITE:PS50118"
FT DNA_BIND 689..757
FT /note="HMG box"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT REGION 290..376
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 560..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 770..808
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1121..1150
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1196..1246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1304..1337
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1359..1383
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1445..1508
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 295..314
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..361
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 563..587
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 600..626
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 776..795
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1127..1150
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1201..1239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1362..1382
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1466..1498
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1508 AA; 162366 MW; E3FD339D22DEEF55 CRC64;
MPRNTSKEVR STLVVDDDDD QLDVVKRPRP QRIPATSGFC NPHALLHKLE VELRSAKSSS
SESLRDDDCI VHQNDVASHS LSLQDWKGTR VLAKPPDRDD YFCGCIKAVR SNNTLVVEFD
EAAGAETLVV YHDVLGSCPF EVVADQAPVP DLVKIGMVVC ARRNADQPNF ELAQVVGVSM
MPVSFQLKFM PNTAPRHAAS VRACVPESDV VFIWVSRANI RLLRPPWFEE LSCETQQRSK
MPVNFSPFLH TGGLPGQHLA INACGSSSFV NNISPSPDCE VDFPMTCQPE GAQRRTSCED
QEEGSRRSSC DCASHEENNS DNSGYGNVSP QSPASPDGNF LHASTAATPA STDSQSTGGE
RCDGAEATGP GGVDNSLLAF KKKHQKGDVM LTPGGIRKKF NGKQWRRLCS KEGCNKESQR
RGYCSRHLSL NGKAYSLDAC CHNASNMLLL SSTDFSFKDN NGTSVDPIEA RLSTAAVLDA
RFESSDDVGH QKPFELAMRN RVDGMAPMTP SAADVLQARG YRAASIQQSL NGDKRGFYLR
SPVGVQDLAC QREGLLSMET DLTGHPNGAS SMNCQAQSGQ VNRRDSGSAQ VRRTKTKHES
LSQIALSPGY EEPSTSVYST SAQQAGSYEE DEDDDDVFNP TAAEMDQTSL DGDSARSLGK
RRAHSLGALP KELSDIKSPK KGVRSKEHIR RPMNAFMIFS KRHRPLVHQR HPNQDNRTVS
KILGEWWYAL GPEQKHEYHN LACQVKEAHF KAHPNWKWCS KEKKHVLKKS EGDNDESSST
FCFDPSGSAE STTERDIDPV NVDGPTGYSS EEKTDLFHGC SANAETQGTG RISPSKVSGT
SCKVRSYLDA SMSTVGGMQP DPAIHHAVES VALRQPSAKL SASAFYSQLQ SMSSAFPIGP
HMLQSLDLSR FGMLAHSDSA AADATLGSDL LHSPILMHSS SVNFPYPVST YASLPRQLSQ
TLQAGASPGG LAFISEPASA GLLPAVRSLN QPVLFSPVGL DMLQRNATRF DLNPSSACVP
PQGPLLSPLV TTSEGELKYL PAFLSPRATS SYGNPLPGSA FSAKSSRFMP VNAETGPDGK
QPSKAPIVAM KAEVSSPNFE RPQIGTQHGK RAAGVDALLP VGESDSRKPC EQSSFDSASS
PAAAVGGSSS DSIVKCSANT TGMSTALSAT CSNGQSVEST QPSPVRFVLA PTPAQLGIAP
GQTKRGSTAN KDKQMASADN EVTQCSTSTS PQEKSCNAEQ PCKGDSAECP KAVFKRQDSN
MDRVLSVVNF GEKFAQLPEF DPDEREGASV PSTPLQIVKT YFDKQKQSGA GPSSESDQTA
QTSPSMSKSA PKTPNRRTGN FFFGANFSLD TLVDPALRRS ENNESESPSL CSPMTPLDGW
NRSNSRKLLD ERRRLVMELF EKEGMFPSAQ ATSQFQMIHS EVFPAKQILQ LKIREVRQKV
MASVQSPATP SLGGTCPAPA TPATPLATPV SVSEASPTSD RCFTPPSPND SLPSEKFAIT
ASQGPPAE
//
