ID A0A085U5P2_YERRU Unreviewed; 358 AA.
AC A0A085U5P2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=Endolytic peptidoglycan transglycosylase RlpA {ECO:0000256|HAMAP-Rule:MF_02071};
DE EC=4.2.2.- {ECO:0000256|HAMAP-Rule:MF_02071};
GN Name=rlpA {ECO:0000256|HAMAP-Rule:MF_02071,
GN ECO:0000313|EMBL:SUP99774.1};
GN ORFNames=CSF007_5455 {ECO:0000313|EMBL:CEK26858.1}, NCTC10476_01024
GN {ECO:0000313|EMBL:SUP99774.1};
OS Yersinia ruckeri.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=29486 {ECO:0000313|EMBL:SUP99774.1, ECO:0000313|Proteomes:UP000255169};
RN [1] {ECO:0000313|EMBL:CEK26858.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CSF007-82 {ECO:0000313|EMBL:CEK26858.1};
RA Nelson M.C., LaPatra S.E., Welch T.J., Graf J.;
RT "Complete Genome Sequence of Yersinia ruckeri Strain CSF007-82, Etiologic
RT Agent of Red Mouth Disease in Salmonid Fish.";
RL Genome Announc. 3:1-2(2015).
RN [2] {ECO:0000313|EMBL:SUP99774.1, ECO:0000313|Proteomes:UP000255169}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC10476 {ECO:0000313|EMBL:SUP99774.1,
RC ECO:0000313|Proteomes:UP000255169};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Lytic transglycosylase with a strong preference for naked
CC glycan strands that lack stem peptides. {ECO:0000256|HAMAP-
CC Rule:MF_02071}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|HAMAP-Rule:MF_02071};
CC Lipid-anchor {ECO:0000256|HAMAP-Rule:MF_02071}.
CC -!- SIMILARITY: Belongs to the RlpA family. {ECO:0000256|HAMAP-
CC Rule:MF_02071, ECO:0000256|RuleBase:RU003495}.
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DR EMBL; LN681231; CEK26858.1; -; Genomic_DNA.
DR EMBL; UHJG01000001; SUP99774.1; -; Genomic_DNA.
DR RefSeq; WP_004720181.1; NZ_VDHI01000014.1.
DR AlphaFoldDB; A0A085U5P2; -.
DR STRING; 29486.UGYR_15150; -.
DR GeneID; 66878825; -.
DR KEGG; yrb:UGYR_15150; -.
DR PATRIC; fig|29486.44.peg.2464; -.
DR eggNOG; COG0797; Bacteria.
DR OrthoDB; 9779128at2; -.
DR Proteomes; UP000255169; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008932; F:lytic endotransglycosylase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0042834; F:peptidoglycan binding; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0000270; P:peptidoglycan metabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd22268; DPBB_RlpA-like; 1.
DR Gene3D; 2.40.40.10; RlpA-like domain; 1.
DR Gene3D; 3.30.70.1070; Sporulation related repeat; 1.
DR HAMAP; MF_02071; RlpA; 1.
DR InterPro; IPR034718; RlpA.
DR InterPro; IPR009009; RlpA-like_DPBB.
DR InterPro; IPR036908; RlpA-like_sf.
DR InterPro; IPR012997; RplA.
DR InterPro; IPR007730; SPOR-like_dom.
DR InterPro; IPR036680; SPOR-like_sf.
DR NCBIfam; TIGR00413; rlpA; 1.
DR PANTHER; PTHR34183; -; 1.
DR PANTHER; PTHR34183:SF1; ENDOLYTIC PEPTIDOGLYCAN TRANSGLYCOSYLASE RLPA; 1.
DR Pfam; PF03330; DPBB_1; 1.
DR Pfam; PF05036; SPOR; 1.
DR SUPFAM; SSF50685; Barwin-like endoglucanases; 1.
DR SUPFAM; SSF110997; Sporulation related repeat; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS51724; SPOR; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475, ECO:0000256|HAMAP-
KW Rule:MF_02071};
KW Cell wall biogenesis/degradation {ECO:0000256|ARBA:ARBA00023316,
KW ECO:0000256|HAMAP-Rule:MF_02071};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00023288, ECO:0000256|HAMAP-
KW Rule:MF_02071};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|HAMAP-Rule:MF_02071};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_02071};
KW Palmitate {ECO:0000256|ARBA:ARBA00023139, ECO:0000256|HAMAP-Rule:MF_02071};
KW Reference proteome {ECO:0000313|Proteomes:UP000255169}.
FT DOMAIN 281..357
FT /note="SPOR"
FT /evidence="ECO:0000259|PROSITE:PS51724"
FT REGION 216..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 358 AA; 37557 MW; E908E635F49BCFA2 CRC64;
MRKEWLWIGV VSVLLSACTN ENQAPIEQAQ QTYNGPVEEI GGAEPRYEPF NPNFNQDYKV
NGQSYSVIKD AQNFSQIGLA SSYGEEANGN TTATGEIFDP NALTAAHPTL PIPSYVRVTN
VSNGRQIVVR VNDRGPYTPG RVIDLSKAAA DRLNISNNTK VKIDFINVAP DGSLSGPGMV
GTTIAKQSYA LPSRPDLASG PMGNPIQQDA PAESVPALPI DNSKLSGDDA AQPVAPQSSG
FLRAPSSVPA GILETTEPVV PAAVSHSGSA ASVAAVAPAA ALASGTYIVQ VGALTDAQRA
ASWQQDLSQR FDVPGKVSSA GNVHRVQLGP FSSRQQATEL QQRLSAEAQQ QSFIIAAP
//
