ID A0A086BLH1_9FLAO Unreviewed; 734 AA.
AC A0A086BLH1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=IQ37_03785 {ECO:0000313|EMBL:KFF29785.1};
OS Chryseobacterium piperi.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales; Weeksellaceae;
OC Chryseobacterium group; Chryseobacterium.
OX NCBI_TaxID=558152 {ECO:0000313|EMBL:KFF29785.1, ECO:0000313|Proteomes:UP000028709};
RN [1] {ECO:0000313|EMBL:KFF29785.1, ECO:0000313|Proteomes:UP000028709}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CTM {ECO:0000313|EMBL:KFF29785.1,
RC ECO:0000313|Proteomes:UP000028709};
RA Pipes S.E., Stropko S.J., Newman J.D.;
RT "Genome of Chryseobacterium piperi CTM.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RecQ subfamily.
CC {ECO:0000256|ARBA:ARBA00005446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFF29785.1}.
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DR EMBL; JPRJ01000003; KFF29785.1; -; Genomic_DNA.
DR RefSeq; WP_034681881.1; NZ_JPRJ01000003.1.
DR AlphaFoldDB; A0A086BLH1; -.
DR STRING; 558152.IQ37_03785; -.
DR KEGG; cpip:CJF12_02715; -.
DR eggNOG; COG0514; Bacteria.
DR OrthoDB; 9763310at2; -.
DR Proteomes; UP000028709; Unassembled WGS sequence.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:InterPro.
DR CDD; cd17920; DEXHc_RecQ; 1.
DR CDD; cd18794; SF2_C_RecQ; 1.
DR Gene3D; 1.10.10.1390; ATP-dependent DNA helicase RecQ; 1.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR004589; DNA_helicase_ATP-dep_RecQ.
DR InterPro; IPR006293; DNA_helicase_ATP-dep_RecQ_bac.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR048671; RecQ-1-like_HTH.
DR InterPro; IPR032284; RecQ_Zn-bd.
DR InterPro; IPR018982; RQC_domain.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR01389; recQ; 1.
DR NCBIfam; TIGR00614; recQ_fam; 1.
DR PANTHER; PTHR13710:SF105; BLOOM SYNDROME PROTEIN; 1.
DR PANTHER; PTHR13710; DNA HELICASE RECQ FAMILY MEMBER; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00570; HRDC; 1.
DR Pfam; PF21220; RecQ-1-like_HTH; 1.
DR Pfam; PF16124; RecQ_Zn_bind; 1.
DR Pfam; PF09382; RQC; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00341; HRDC; 1.
DR SMART; SM00956; RQC; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50967; HRDC; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KFF29785.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000028709}.
FT DOMAIN 29..200
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 220..366
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 537..617
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
SQ SEQUENCE 734 AA; 83209 MW; D9CC7E08744E47BB CRC64;
MSAKKATLSG ELKKYFGFST FKGQQEQIIE NLLEGKDIFV LMPTGGGKSL CYQLPALISE
GTAIVVSPLI ALMKNQVDAV NGLSSDDGIA HVLNSSLNKT QTKQVFDDIK SGKTKLLYVA
PESLIKEDYL DFFKEVKISF FAIDEAHCIS EWGHDFRPEY RNLKTIIDKI ADVPVIALTA
TATPKVQDDI QKTLGMTNAL VFKESFNRAN LYYEVRPKVN IDREVVRFIN QNKGKSGIIY
CLSRRKVEEL AQLLQVNGIN ALPYHAGLDQ KVRVANQDKF LMEEADVIVA TIAFGMGIDK
PDVRFVIHYD FPKSLESYYQ ETGRAGRDGG EGYCLAFYDP KDIEKLEKFL AQKPVSEREI
GLQLLNEVVG YAETSMSRRQ YILYYFGETF DPVKGDGANM CDNASNPPKL KDATEDLKKV
LKLINETGEK FKSKDLISVI VGKESAVTKS YKLEQTSYFG FGKDEKDNYW KTILRQATVQ
NFLQKDIETY GVLKISEKGL KVLDGKLEHS FLIAEDREFD LTQTKAESDQ VQMQAGGSLD
QNLFTQLKEL RKKVAKKYGI PPYTVFMDPS LEDMTIQYPV TVEEITKIYG VGEGKAKKYG
KEFADFIKTY VEDNNIECTH DMILKQVANK SSHKVFIIQS TDKKIDLEDI ARAKNLTMNE
LLKEMESIVY QGTKLNIDYY IEDNFDEDIV DGFMEFMNES ESDSMKVLLD EFGDELSDEE
VRMLRIKFIS DVAN
//
