ID   A0A086D524_9GAMM        Unreviewed;       820 AA.
AC   A0A086D524;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   RecName: Full=LPS-assembly protein LptD {ECO:0000256|HAMAP-Rule:MF_01411};
DE   Flags: Precursor;
GN   Name=lptD {ECO:0000256|HAMAP-Rule:MF_01411};
GN   ORFNames=GY26_07455 {ECO:0000313|EMBL:KFF49538.1};
OS   Gammaproteobacteria bacterium MFB021.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria.
OX   NCBI_TaxID=1492922 {ECO:0000313|EMBL:KFF49538.1, ECO:0000313|Proteomes:UP000028732};
RN   [1] {ECO:0000313|EMBL:KFF49538.1, ECO:0000313|Proteomes:UP000028732}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MFB021 {ECO:0000313|EMBL:KFF49538.1,
RC   ECO:0000313|Proteomes:UP000028732};
RA   Joseph T.C., Baby A., Varghese A.M., Reghunathan D., Murugadas V.,
RA   Lalitha K.V.;
RT   "Draft Genome sequence of a halophilic and highly halotolerant unknown
RT   Gammaproteobacteria strain MFB021.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Together with LptE, is involved in the assembly of
CC       lipopolysaccharide (LPS) at the surface of the outer membrane.
CC       {ECO:0000256|HAMAP-Rule:MF_01411}.
CC   -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC       complex. Interacts with LptE and LptA. {ECO:0000256|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000256|HAMAP-
CC       Rule:MF_01411}.
CC   -!- SIMILARITY: Belongs to the LptD family. {ECO:0000256|HAMAP-
CC       Rule:MF_01411}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|HAMAP-Rule:MF_01411}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFF49538.1}.
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DR   EMBL; JNVT01000059; KFF49538.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A086D524; -.
DR   STRING; 1492922.GY26_07455; -.
DR   eggNOG; COG1452; Bacteria.
DR   OrthoDB; 9760225at2; -.
DR   Proteomes; UP000028732; Unassembled WGS sequence.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR   GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR   HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR   InterPro; IPR020889; LipoPS_assembly_LptD.
DR   InterPro; IPR007543; LptD_C.
DR   InterPro; IPR005653; OstA-like_N.
DR   PANTHER; PTHR30189; LPS-ASSEMBLY PROTEIN; 1.
DR   PANTHER; PTHR30189:SF1; LPS-ASSEMBLY PROTEIN LPTD; 1.
DR   Pfam; PF04453; LptD; 1.
DR   Pfam; PF03968; LptD_N; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane {ECO:0000256|ARBA:ARBA00023237, ECO:0000256|HAMAP-
KW   Rule:MF_01411};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01411};
KW   Signal {ECO:0000256|HAMAP-Rule:MF_01411}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT   CHAIN           21..820
FT                   /note="LPS-assembly protein LptD"
FT                   /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT                   /id="PRO_5008982419"
FT   DOMAIN          66..199
FT                   /note="Organic solvent tolerance-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03968"
FT   DOMAIN          316..729
FT                   /note="LptD C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04453"
SQ   SEQUENCE   820 AA;  93764 MW;  30B2704197ACD00F CRC64;
     MGKRLVWTAL TGVISSTAQA APPAPLPADQ LDWVPWGDQA PAGALCGGRY VQPGYLLPEG
     RTPEEVLSNS ATAEYGDNGE TILGGEVVLR RGDSQLQAPQ VRVNAARDTA FADGPLTIRY
     PGLLVRGDDG QVSLDSDAAR IDDAHYVIHD QRVRGDAQAL QRLDDGRYRM REASFTTCAP
     DSRLWRIVGS DVTIDRAQGY GTATNARLEM GDVPVFYWPW VRFPVDDRRQ SGFLWPTLGL
     SSDGLDYSQP YYLNLAPNYD ATITPRVITD HGLLMGGEFR YLFGSDRGTI DGAYLANDNG
     GNNDNPNDPK DAFDGKDRWF VDYQHYGYFT DRLDYALRYG AASDGRYFDD FGSNFAEQDT
     EYLERLARLS YQGTTWYLDA RAQGYQRMQY PIDENDRPYY RLPSLTANAR WQQESGFYQE
     WNSNATYFWR DLHGVDAQGN WFDEDENRTR NIPLRESANG SRLNLTPAIG WRAQPSWGFL
     EPRFQLWQTN YELDYGNRDT SRDETLSRTV PVYSLDSGLI FQRDVTAFDQ GFKQTFEPRL
     YYAYVPERDQ SEYPVFDTDE QAISWSQLWS PYRFTGADRV GDVNKLSYGA STRFLEDDTG
     RERLALSVGQ SAYFEDRNVT LLDDSDNLTP AQRRYDDYRR TRDRSPVITQ LDWRINDQWR
     SRYEWFYDDQ RSQTEKASAY LQYLSPAGHV LNLGYRWQLQ GFDPASDADD QLSYNREDFD
     VSFAYKATSS LDLIGRYLYD NTNKRDLETL AGVQFNSCCS AVQVVWREWV DDNDTAYTID
     DDYTDRGLFL RFVFKGLGGV GQNADSYFAS AVPGYEPTTF
//