ID   A0A086D5F7_9GAMM        Unreviewed;       397 AA.
AC   A0A086D5F7;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Aldehyde dismutase {ECO:0000313|EMBL:KFF49671.1};
GN   ORFNames=GY26_06740 {ECO:0000313|EMBL:KFF49671.1};
OS   Gammaproteobacteria bacterium MFB021.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria.
OX   NCBI_TaxID=1492922 {ECO:0000313|EMBL:KFF49671.1, ECO:0000313|Proteomes:UP000028732};
RN   [1] {ECO:0000313|EMBL:KFF49671.1, ECO:0000313|Proteomes:UP000028732}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MFB021 {ECO:0000313|EMBL:KFF49671.1,
RC   ECO:0000313|Proteomes:UP000028732};
RA   Joseph T.C., Baby A., Varghese A.M., Reghunathan D., Murugadas V.,
RA   Lalitha K.V.;
RT   "Draft Genome sequence of a halophilic and highly halotolerant unknown
RT   Gammaproteobacteria strain MFB021.";
RL   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFF49671.1}.
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DR   EMBL; JNVT01000053; KFF49671.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A086D5F7; -.
DR   STRING; 1492922.GY26_06740; -.
DR   eggNOG; COG1063; Bacteria.
DR   OrthoDB; 9773078at2; -.
DR   Proteomes; UP000028732; Unassembled WGS sequence.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:UniProt.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd08282; PFDH_like; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR002328; ADH_Zn_CS.
DR   InterPro; IPR007698; AlaDH/PNT_NAD(H)-bd.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR014184; HCHO_DH_non_GSH.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   NCBIfam; TIGR02819; fdhA_non_GSH; 1.
DR   PANTHER; PTHR42813:SF3; GLUTATHIONE-INDEPENDENT FORMALDEHYDE DEHYDROGENASE; 1.
DR   PANTHER; PTHR42813; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF01262; AlaDh_PNT_C; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00059; ADH_ZINC; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          36..145
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          182..240
FT                   /note="Alanine dehydrogenase/pyridine nucleotide
FT                   transhydrogenase NAD(H)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01262"
SQ   SEQUENCE   397 AA;  41819 MW;  598FEF36E7927B7E CRC64;
     MSSPANRGVV YRGPGKVAVE NIAFPELALG SRQCQHGVIL KVLTTNICGS DQHMVRGRTT
     APEGLVLGHE ITGEVVECGR DVEFIKVGDV VSVPFNVACG RCRNCKRGDT HICLNVNGDR
     AGGAYGYVDM GGWVGGQAEY VMVPYADFQL LVFPDKEQAL EKILDLTMLS DIFPTGFHGC
     VTAGVKPGST VYIAGAGPVG LAAAVSAQLL GAACVIVGDM NDQRLEQARS FGCEGLDLKQ
     DASMSDLIES VLGVPEVDCA VDAVGFEANC HGHNHAHEQP ATVLNATMEI TQAGGAVGIP
     GLYVTEDPGA ESEDAKHGNI SMKFGLGWAK AMSFHTGQTP AMRYQRQLMQ AILHERVHIG
     KAVNVQTISL DDAPKGYAAF DGGAAKKFVI DPHGTLG
//