ID   A0A086GIG1_STRSC        Unreviewed;       866 AA.
AC   A0A086GIG1;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=Lyase {ECO:0000313|EMBL:KFF95178.1};
GN   ORFNames=IQ62_43545 {ECO:0000313|EMBL:KFF95178.1};
OS   Streptomyces scabiei.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1930 {ECO:0000313|EMBL:KFF95178.1, ECO:0000313|Proteomes:UP000028722};
RN   [1] {ECO:0000313|EMBL:KFF95178.1, ECO:0000313|Proteomes:UP000028722}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NCPPB 4086 {ECO:0000313|EMBL:KFF95178.1,
RC   ECO:0000313|Proteomes:UP000028722};
RA   Harrison J., Sapp M., Thwaites R., Studholme D.J.;
RT   "Genome sequencing of plant-pathogenic Streptomyces species.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the beta-eliminating lyase family.
CC       {ECO:0000256|ARBA:ARBA00009721}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFF95178.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JPPX01000271; KFF95178.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A086GIG1; -.
DR   OrthoDB; 513465at2; -.
DR   Proteomes; UP000028722; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:InterPro.
DR   GO; GO:0009820; P:alkaloid metabolic process; IEA:InterPro.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   GO; GO:0009058; P:biosynthetic process; IEA:UniProt.
DR   CDD; cd13930; PT-Tnase; 1.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR   InterPro; IPR033964; Aro_prenylTrfase.
DR   InterPro; IPR017795; Aro_prenylTrfase_DMATS.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR32325; BETA-ELIMINATING LYASE-LIKE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR32325:SF4; TRYPTOPHANASE; 1.
DR   Pfam; PF01212; Beta_elim_lyase; 1.
DR   Pfam; PF11991; Trp_DMAT; 1.
DR   SFLD; SFLDS00036; Aromatic_Prenyltransferase; 1.
DR   SFLD; SFLDG01162; I; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:KFF95178.1};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          453..828
FT                   /note="Aromatic amino acid beta-eliminating lyase/threonine
FT                   aldolase"
FT                   /evidence="ECO:0000259|Pfam:PF01212"
SQ   SEQUENCE   866 AA;  94317 MW;  BBFBACFBB6E89799 CRC64;
     MSATGSGTGR TRRDRTLGEL VTGQLLRLCQ ASGLARTDAE TYAHVLTDSL GAVAERSLDL
     PPPSRSFLSD DSTPVEFSLS FTPDAPPRVR VLLEPGCGAD SLRENGRAGM RVVRSMARRW
     GFATEQLDAL EDLFLPPDPQ GPLALWIALE LSPGGVPKVK VYLNPAATGA RRAAETVREA
     LDRLGHRQAF GMLPSADGYP FFALDLGDWA APRVKIYATH HGLPVTGTGG LCRMESGPDS
     ETLEEFLRTA GGFGDGTGQP QAPEARFDRR PVLTCHSFTR TTGGPTGFTL HVPVRDYARD
     DGEALRRAGT VLGRHGLETG ALDRPLAAVT PRPLRDGAGL IAYVALAHEQ NQPPRVTTYI
     SSEAYEVRAP NTPSENTPSL DRPTPSYGRF EFGRRHSNDE AIRSTSGARI SMEPYRIKVV
     EPIALTTRQQ REAALERVHY NLFDLRAEEV TIDLLSDSGT GAISAAQLAA GMEGDESYAG
     SRSFYRFHET VTELTGYRHI LPAHQGRAAE RILFNTLLEP GGIVLANTHF DTTRANVELS
     GCQAHDIPCA EARDLDSKRP FKGNIDLDAL RTALEGPDGS RVRVVIMTIT NNGGGGQPVS
     MENLKQTAEI CRRHGVPMIL DAARFAENAW LVTRHEEAYR DRTPRQVAEE AFRLADGCVM
     SAKKDGIVHI GGFIGLNDPE LAEKCERLLI ATEGFATYGG LAGRDLDMMA TGLLEVTEPA
     YLAERADVAS HLADRVRSAG VDILEPPGLH ALYLNAGRLL PHIPPHHYPG HALACRLYLE
     GGIRSAELGS LYLGEEDEDG NPVKSAPYEL VRLALPRRVY TRSHYDHVGR TLEQIAKEAE
     SVHGYRIVEQ SPILRHFRAK LQPVTG
//