ID A0A086H2A8_STRSC Unreviewed; 274 AA.
AC A0A086H2A8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=IclR family transcriptional regulator {ECO:0000313|EMBL:KFG01776.1};
GN ORFNames=IQ62_06430 {ECO:0000313|EMBL:KFG01776.1};
OS Streptomyces scabiei.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1930 {ECO:0000313|EMBL:KFG01776.1, ECO:0000313|Proteomes:UP000028722};
RN [1] {ECO:0000313|EMBL:KFG01776.1, ECO:0000313|Proteomes:UP000028722}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 4086 {ECO:0000313|EMBL:KFG01776.1,
RC ECO:0000313|Proteomes:UP000028722};
RA Harrison J., Sapp M., Thwaites R., Studholme D.J.;
RT "Genome sequencing of plant-pathogenic Streptomyces species.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFG01776.1}.
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DR EMBL; JPPX01000047; KFG01776.1; -; Genomic_DNA.
DR RefSeq; WP_037690894.1; NZ_KL997399.1.
DR AlphaFoldDB; A0A086H2A8; -.
DR OrthoDB; 8479143at2; -.
DR Proteomes; UP000028722; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF24; HTH-TYPE TRANSCRIPTIONAL REPRESSOR ALLR; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 26..87
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 88..274
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 274 AA; 29419 MW; 71ED28BFAEAF28CE CRC64;
MKHTQPDEGP TDLGEDGPTG AGDNRLVGSD RVLAVLRELA RYPDGVGLDE LTRVIGSPKP
TVHRALGALR RAGLAEQDAG SRYVLGDEFL RMAFAHHEAR PEHLRVRPVL ETLAHRFGET
AHYAVLDGHE VVYRAKVDPP AGAVRLTSTI GGRNPAHSTA VGKLLLSARL GSLEEVEAWR
GGSPLERRTP RTRCAVADLH RELGATRARG YGVDDQENET GVNCLALPVF LTSPTVPSGA
VSVSALAYRT PLASLVDALD EIRALLGRLG EPHR
//
