ID A0A086MY24_9ACTN Unreviewed; 441 AA.
AC A0A086MY24;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Metal-dependent phosphohydrolase {ECO:0000313|EMBL:KFG73792.1};
GN ORFNames=FM21_23690 {ECO:0000313|EMBL:KFG73792.1};
OS Streptomyces mutabilis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=67332 {ECO:0000313|EMBL:KFG73792.1, ECO:0000313|Proteomes:UP000029095};
RN [1] {ECO:0000313|EMBL:KFG73792.1, ECO:0000313|Proteomes:UP000029095}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TRM45540 {ECO:0000313|EMBL:KFG73792.1,
RC ECO:0000313|Proteomes:UP000029095};
RA Luo X., Zhang L.;
RT "Complete genome sequence of the Streptomyces mutabilis TRM45540.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFG73792.1}.
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DR EMBL; JNFQ01000002; KFG73792.1; -; Genomic_DNA.
DR RefSeq; WP_043380123.1; NZ_KN039947.1.
DR AlphaFoldDB; A0A086MY24; -.
DR STRING; 1915400.FM21_23690; -.
DR HOGENOM; CLU_000445_92_14_11; -.
DR Proteomes; UP000029095; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR006675; HDIG_dom.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR45228:SF1; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186; 1.
DR PANTHER; PTHR45228; CYCLIC DI-GMP PHOSPHODIESTERASE TM_0186-RELATED; 1.
DR Pfam; PF13487; HD_5; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
DR PROSITE; PS51832; HD_GYP; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:KFG73792.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..41
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 220..415
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
FT DOMAIN 242..364
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
FT REGION 410..441
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 441 AA; 47392 MW; 9D5D1FCB5155E1F2 CRC64;
MDAVPARARA YVSGVVLLAL VCLCPLPVVH TPWWAVLLLA GLYAGSELVA RSRSVGTCYP
VLLAGAFLLP PPAAALVALP GAMLSPVTQR PFVLRRVWRA ALLTLAVWAA ARVHWECGGR
DAVVAPDFPY ALVPAGAAVL AFCLVLTLLD GGILYLADRV PARRAWRGLF SRSLGPIAVH
GLAGLMMAVL WRSPYGFVAA LFVLLPMCVA WWAFAQYHRE QAAHQATIRA LVQAVDIKDG
YTRGHSERVG RASMMIAREL GMDDERVETL RFAGILHDVG KLGVPTRLLR KDGPLTPEER
RVIELHPEYG HEMVRGIRFL GEARAAVLHH HERLDGSGYP YGLAGDRIPE SARVVAVADA
FDAMTSTRSY SRARPVEVAV AELQRCAGAQ FDPRMVGALV RALGRHGWHP AVTSDGGPPL
PAGVPAGRTG EARDSVGKGA S
//
