ID A0A086Y042_9RHOB Unreviewed; 829 AA.
AC A0A086Y042;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Diguanylate cyclase {ECO:0000313|EMBL:KFI27642.1};
DE SubName: Full=FAD-dependent oxidoreductase {ECO:0000313|EMBL:QBJ24029.1};
GN ORFNames=CN97_00075 {ECO:0000313|EMBL:KFI27642.1}, HmaOT1_07020
GN {ECO:0000313|EMBL:QBJ24029.1};
OS Haematobacter massiliensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Haematobacter.
OX NCBI_TaxID=195105 {ECO:0000313|EMBL:KFI27642.1, ECO:0000313|Proteomes:UP000028826};
RN [1] {ECO:0000313|EMBL:KFI27642.1, ECO:0000313|Proteomes:UP000028826}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG 47968 {ECO:0000313|EMBL:KFI27642.1,
RC ECO:0000313|Proteomes:UP000028826};
RA Wang D., Wang G.;
RT "Genome of Haematobacter massiliensis CCUG 47968.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:QBJ24029.1, ECO:0000313|Proteomes:UP000291082}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OT1 {ECO:0000313|EMBL:QBJ24029.1,
RC ECO:0000313|Proteomes:UP000291082};
RA Lee K.;
RT "The first complete genome sequence of Haematobacter massiliensis OT1
RT isolated from human skin.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
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DR EMBL; JGYG01000010; KFI27642.1; -; Genomic_DNA.
DR EMBL; CP035510; QBJ24029.1; -; Genomic_DNA.
DR RefSeq; WP_035712725.1; NZ_NIPY01000063.1.
DR AlphaFoldDB; A0A086Y042; -.
DR STRING; 195105.CN97_00075; -.
DR KEGG; hml:HmaOT1_07020; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0665; Bacteria.
DR OrthoDB; 7156675at2; -.
DR Proteomes; UP000028826; Unassembled WGS sequence.
DR Proteomes; UP000291082; Chromosome.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000028826}.
FT DOMAIN 7..380
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 384..436
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 440..718
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 741..819
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 829 AA; 92174 MW; B53A9B0B35A0B9F2 CRC64;
MKTHVRALVV GGGAVGTAIA YHLARAGWDT MLLERDELTS GSTWHAAGLL PLFNMGYATS
HIHDYSVRFY KTLEEETGLN PGFAIVGNLR MAQTEARMDE YRLYSATAEA VGIEHVFLTP
QQIAERWPLV RAEDLKGALF HPTDGYINPA DVTQAMARGA RLHGATIERR WQVDGYRWTG
REWIVTATKM VERGGNLVPS EERVEITAEH VVTATGNHAQ RTARLLGLKI PAIPVEHQYI
VTEPDLALVD WRRAGNPEHP VLRDADAKWY VREERGGWIL GPYERGAPAR FAYDVPESFR
ADLFPLALDR IEEEYAAMLH RIPSSEAAGL KDDFNGPICY TPDGNPLVGP APGLRNMWLA
EGFSFGITAA GGTGHYLAQL MTAGEAEIDM ASLDPRRYGD WMTTEYAVRK NEECYEHVFI
LHHPDEEREA ARPLRTAPAY DRQKAAGAQF GQVNGWERPN YYAPPGFDDH AARSFRRGGW
WQYARAEAEA VRSAAGLIDA SAFAKHLVRG PGATAFLDWF TTNRLPKVGR IGLTYALTPT
GTVRSEYTIV RLAEDAYYLV SAGAWAAYDG DWLRKCAEDR AAEFGWIDIH DITTQWGVFA
LAGPASRDIL KALIRDAEPE TALSNKRFPW LSMREVELGM CPVRAIRVAY TGELGWELHH
PIEMQTYLWD RLMEAGQPHG LKLVGARAQN WLRQEKSYRA FGTELGRDAT PLEAGVERFV
DLSKQFQGRE AMEAAPLRAT CVTLLIDGPA DADPWGREAL WRDGRVVGRL TSGGWSVAFG
KSIGMGYVEP GLAMPGTRLD VRMGGKLWPA EVTQDSPYDP ANARIRADG
//
