ID A0A087CRG0_9BIFI Unreviewed; 683 AA.
AC A0A087CRG0;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Sodium/hydrogen exchanger {ECO:0000313|EMBL:KFI85860.1};
GN ORFNames=BREU_1043 {ECO:0000313|EMBL:KFI85860.1};
OS Bifidobacterium reuteri DSM 23975.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=1437610 {ECO:0000313|EMBL:KFI85860.1, ECO:0000313|Proteomes:UP000028984};
RN [1] {ECO:0000313|EMBL:KFI85860.1, ECO:0000313|Proteomes:UP000028984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23975 {ECO:0000313|EMBL:KFI85860.1,
RC ECO:0000313|Proteomes:UP000028984};
RA Ventura M., Milani C., Lugli G.A.;
RT "Genomics of Bifidobacteria.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFI85860.1}.
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DR EMBL; JGZK01000006; KFI85860.1; -; Genomic_DNA.
DR RefSeq; WP_044088570.1; NZ_JGZK01000006.1.
DR AlphaFoldDB; A0A087CRG0; -.
DR STRING; 1437610.BREU_1043; -.
DR eggNOG; COG0025; Bacteria.
DR OrthoDB; 9809206at2; -.
DR Proteomes; UP000028984; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015385; F:sodium:proton antiporter activity; IEA:InterPro.
DR Gene3D; 6.10.140.1330; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR018422; Cation/H_exchanger_CPA1.
DR PANTHER; PTHR10110; SODIUM/HYDROGEN EXCHANGER; 1.
DR PANTHER; PTHR10110:SF86; SODIUM_HYDROGEN EXCHANGER 7; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028984};
KW Sodium {ECO:0000256|ARBA:ARBA00023053};
KW Sodium transport {ECO:0000256|ARBA:ARBA00023201};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..103
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..201
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 276..296
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 353..379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 391..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 10..411
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 683 AA; 76476 MW; D3445E4C03B4727D CRC64;
MENAILVTEI LFAILISSFL SRFLPKISTP LIQIAFGVAW YFTPGLRNIQ FEPDMFMLLF
IVPLFYLEAR NIDRKALRKD LSLSLSLAVG LVMVTMALSG VALHELWPAI PMMAAVAMGA
IISPTDAVSV AQLGGVVKLT PRQQSVLQSE SLLNDPVSLV GFQTMLVALA TGHFSPAGFG
WQVLMSFVLG TLIGAVVGWL FDRLVLFMRK HNFEDVTTRM LMECFLPFGV YLLSEHVGIS
GLLAVVACGV VITFPRTGVG GDVARVNLVS NSVWHFVDFT LNGMVFVLLG IELPIAMRAI
WDDPRVDLGA MIGLVLLLTL LTLVLRFIWC VGTLRWAKDL ATGKRRKMTR ERWHSAVVMT
FGGPKGAISL AMAFSLPYSV DNGASVPVRN IILFIVSGYI VLSIVISNVM LPLLSPKPAD
TSKEEWAKRD IEMLRRTIAK IVDNETPETH AAVTRVLKSY NDRIERVEAN MPSASPREAN
ELRIRTLRWE RDWLNKAIAT RENVVNPDQE TITQLTGARY LLEHVESVLE RLTPEGGSGH
GLRFNMAKLR RRFMPVIRRF WEGIARRTPG LEAERTRAIR AVQVPLYNDI MERLQDLILD
HVYDAELVAE LLIEYRRALN QILDNSMSPL HAADSSKVEA VRANALRMEL DTIREMLEAK
EITREDARLM RSNVYLMQAE SVV
//
