ID A0A087CYD2_9BIFI Unreviewed; 1972 AA.
AC A0A087CYD2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Endo-alpha-N-acetylgalactosaminidase {ECO:0000313|EMBL:KFI88282.1};
DE EC=3.2.1.97 {ECO:0000313|EMBL:KFI88282.1};
GN ORFNames=BREU_0385 {ECO:0000313|EMBL:KFI88282.1};
OS Bifidobacterium reuteri DSM 23975.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=1437610 {ECO:0000313|EMBL:KFI88282.1, ECO:0000313|Proteomes:UP000028984};
RN [1] {ECO:0000313|EMBL:KFI88282.1, ECO:0000313|Proteomes:UP000028984}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 23975 {ECO:0000313|EMBL:KFI88282.1,
RC ECO:0000313|Proteomes:UP000028984};
RA Ventura M., Milani C., Lugli G.A.;
RT "Genomics of Bifidobacteria.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFI88282.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JGZK01000001; KFI88282.1; -; Genomic_DNA.
DR RefSeq; WP_044089801.1; NZ_JGZK01000001.1.
DR STRING; 1437610.BREU_0385; -.
DR eggNOG; COG0366; Bacteria.
DR eggNOG; COG1196; Bacteria.
DR Proteomes; UP000028984; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0033926; F:glycopeptide alpha-N-acetylgalactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0050110; F:mucinaminylserine mucinaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR CDD; cd14244; GH_101_like; 1.
DR Gene3D; 2.60.120.870; -; 1.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 1.20.1270.90; AF1782-like; 2.
DR Gene3D; 2.60.40.1120; Carboxypeptidase-like, regulatory domain; 1.
DR Gene3D; 1.20.1270.70; Designed single chain three-helix bundle; 2.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 3.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR013784; Carb-bd-like_fold.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR025706; Endoa_GalNAc.
DR InterPro; IPR000421; FA58C.
DR InterPro; IPR040633; Gal_mutarotas_3.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR049314; GH101_dom-5.
DR InterPro; IPR040502; GH101_dom-6.
DR InterPro; IPR040575; GH101_N.
DR InterPro; IPR035364; Glyco_hyd_101_beta.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR048842; SpGH101_helical.
DR Pfam; PF13620; CarboxypepD_reg; 1.
DR Pfam; PF00754; F5_F8_type_C; 1.
DR Pfam; PF07554; FIVAR; 3.
DR Pfam; PF18080; Gal_mutarotas_3; 1.
DR Pfam; PF17974; GalBD_like; 1.
DR Pfam; PF21466; GH101_dom-5; 1.
DR Pfam; PF17995; GH101_N; 1.
DR Pfam; PF17451; Glyco_hyd_101C; 1.
DR Pfam; PF12905; Glyco_hydro_101; 1.
DR Pfam; PF20909; SpGH101_helical; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF49452; Starch-binding domain-like; 1.
DR PROSITE; PS50022; FA58C_3; 1.
PE 4: Predicted;
KW Glycosidase {ECO:0000313|EMBL:KFI88282.1};
KW Hydrolase {ECO:0000313|EMBL:KFI88282.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028984};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..1972
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001819729"
FT TRANSMEM 1946..1966
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1534..1638
FT /note="F5/8 type C"
FT /evidence="ECO:0000259|PROSITE:PS50022"
SQ SEQUENCE 1972 AA; 211261 MW; 98784DDF7C31FAE6 CRC64;
MKKTISVALA TALALTCMGS GGTAFASPLT DADIQSLASQ IQKINDDAST QTPAVQNDSA
ADSSADAATD AVEGWTIDAN IAKGGEILAM EDGWLHFKST AAHGNAAANP SAANDWPAVA
IWGTDYDFSK AGSFHATIKS PQEGSANRFG FYLGYNDPGS GLFIGYDAQG WFWQTYTGGG
EGDWYSGGRI AAPSANDEHD VVVSWTDAKV ATLTVDGQKA FDVDYSKMTN LSNKLAIKAG
SWKLLNQVTD VYIKDFPEVT EAAKYAVSGK VVDAEGAAIA GAAVRLGDAK AKTGEDGGFS
FADVEAGEYT LSVAKDGYED VSQQVTVSDA DLAIDPIVLT KSAAVKTETL KTKKMEVQVK
QNFPAVLQYT MADGKVMYGQ TKDVRTVQIN GTNIELADDD VTFKKVSATE ATYTLKVKDE
AKKIDAVITV EIKVEKNQLH LNVTKIKNNL SDGIPEGNGV EKNAIETLAF PNQSLVSVRA
NQDSAQFTGT TMSSSTTKPG DENFVITDDT SYTDRDYTYG FVSGAGLSAG LWSNSEHDGR
AAYAGVRGGS QNTRVYATTQ QTGETTSFGL ASAPWYYHRT VTDSKGKKYT VAETAMPQMS
VAIAGDENED GVVNWQDGAI AYRDIMNNPY KSEEVPELVA WRIAMNFGSQ AQNPFLTTLD
NVKKVALNTD GLGQSVLLKG YGNEGHDSGH PDYGDIGQRI GGAEDMNTLM TEGAEYGARF
GIHVNASEMY PEAKAFSEDM VRRNAAGGLS YGWNWLDQGI GIDGIYDLAS GSRLSRFAEL
KDEVGDNMDF IYLDVWGNLT SSSSEDSWET RKMSKMINDN GWRMTTEWGS GNEYDSTFQH
WAADLTYGGK DLKGENSEVM RFLRNHQKDS WVGDYPSYGG AANAPLLGGY NMKDFEGWQG
RNDYAAYIEN LFTHDVSTKF IQHFKVTRWV NNPLLTSDNG NANAVTDPNT NNGNEQITLK
DSNGNVVVLS RGSNDASSAA YRQRTITLNG KVVASGEVSA GDGSATGDES YLLPWVWDSS
TGEVVKSSDE KLYHWNTKGG TTTWTLPDSW KNLSSVKVYQ LTDQGKTNEQ TVAVSGGQVT
LTADAETPYV VYQGEAKQIT VNWSEGMHVV DAGFNGGSDT LKSNWTVTGI GKAEVEGENN
AMLRLSGKVS VAQRLTDLKA GQKYALYVGV DNRSTGEASV TVTSGGKVLA TNATGKSIAK
NYIKAYGHNT NSNTEDGSSY FQNMYVFFTA PENGDATVTL SRNSTDEAHT YFDDVRIVEN
DYSGITYDED GGLKSLTNGF EKNAQGIWPF VVSGSEGVED NRVHLSELHA PYTQAGWDVK
KMDDVLDGTW SVKINGLSQK GTLVYQTIPQ NVQFEPGAKY KVSFDYQSGS DDIYAIAVGQ
GEYSASNVKL TNLKKALGET GKAEFELTGG VNGDSWFGIY STSTAPDTQS TTGNAANFGG
YKDFVLDNLK IERVASETRT KAEASDKLKE IQGKFDGKQS EVSEAAWQTY QNALVKARVL
INKDGATADD FTKAYDLLVA LAEYMETAPG NESSDKYDVA MDGSDQLGGY DVEVGSAQSN
YGDYEGPKEF AQDGSASTYW HTNWSENAVG NGTAWYQFNL NEPTTINGLR YLPRPGGATV
NGKILGYRIL LTLADGSTKE VTGEFTYDTA WQKASFDAVD DVVSVRLIAL SSTGSGANQV
NTFASASELR LTTNREVAPE ETVVDKSDLK DALAQANALK ESDYTAVTWS ALIKARDAAQ
TVADDDKASA YDVALATANL GTAIAGLEQK GEEPGPGPVV VDKTDLQNTV NKAESLKESD
YTAESWKVFA AAMGSAKQVL ANEQATQGEV NTALADLQDA IAGLKGSMPD PGPEPEPEPG
AVDKTTLNAT INKAAAINLA LYTDDSANAV RAALKKARAV ADDADATQKQ VDEARTALEK
AIAALVKRGN ASDKGDGNIS DTGANVAMVA LAGLLLAGAG ATLAYCRRRG RI
//
