ID A0A087DJ52_9BIFI Unreviewed; 765 AA.
AC A0A087DJ52;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=exo-alpha-sialidase {ECO:0000256|ARBA:ARBA00012733};
DE EC=3.2.1.18 {ECO:0000256|ARBA:ARBA00012733};
GN ORFNames=BSCA_0584 {ECO:0000313|EMBL:KFI95552.1};
OS Bifidobacterium scardovii.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=158787 {ECO:0000313|EMBL:KFI95552.1, ECO:0000313|Proteomes:UP000029033};
RN [1] {ECO:0000313|EMBL:KFI95552.1, ECO:0000313|Proteomes:UP000029033}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 21589 {ECO:0000313|EMBL:KFI95552.1,
RC ECO:0000313|Proteomes:UP000029033};
RA Ventura M., Milani C., Lugli G.A.;
RT "Genomics of Bifidobacteria.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 33 family.
CC {ECO:0000256|ARBA:ARBA00009348}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFI95552.1}.
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DR EMBL; JGZO01000002; KFI95552.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087DJ52; -.
DR STRING; 158787.BSCA_0584; -.
DR eggNOG; COG4409; Bacteria.
DR Proteomes; UP000029033; Unassembled WGS sequence.
DR GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR CDD; cd15482; Sialidase_non-viral; 1.
DR Gene3D; 2.120.10.10; -; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR011040; Sialidase.
DR InterPro; IPR026856; Sialidase_fam.
DR InterPro; IPR036278; Sialidase_sf.
DR InterPro; IPR023364; Trans_sialidase_dom3.
DR PANTHER; PTHR10628; SIALIDASE; 1.
DR PANTHER; PTHR10628:SF25; SIALIDASE-1; 1.
DR Pfam; PF13088; BNR_2; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50939; Sialidases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000313|EMBL:KFI95552.1};
KW Hydrolase {ECO:0000313|EMBL:KFI95552.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000029033};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 504..734
FT /note="Sialidase"
FT /evidence="ECO:0000259|Pfam:PF13088"
SQ SEQUENCE 765 AA; 83513 MW; 0E37E9A68F731F9E CRC64;
MKGARMTHLS HHIDRAWSTA SLPESGGTLR ATFRISSDGA LLEAKAAERL VLGVSVACGS
LRIEAPEEGI VLDVEDTYGV QLGGVHDLHV TFGDFGTRIY VDGYQAFACA TNICPSKYAR
KGMFVCADEP GMRVERVECF AQAWTSERIQ RNVPIPQPDI EFAAAYVAGK DIVALRAMKT
GTVHAQFRVR GLGQFGTIVA ARTAEGQVLD VSIDDDGFVY RVLANGEWCE YRAFGSWNDG
GWHDLVVRAF RGAIDIYVDG NMEIHQPGQV FFADYPDLRH VSIGEDSFGV RLCGEVRSGG
IYAYPLMDGQ IRKLSDVPPT TDTALFDKGY EGSASYRIPS LAVTPSGVTI AGADRRVVIS
NDAPNEIHFV IRRSLDGGQT WLPLQTVIAF PGSGLDGACV IDSCMVCDRE TGRVSVLVDH
FPGGRGFANV QRGIGLDEQG RLILHDSKGL EYLLRSDGIV TSRDGDATSY RVDDDGNVTC
GGAPAGNIYL KEGADPCESL LTARTSYVVE VHSDDDGETW SNPRHINHMI KEPWMGFLGT
SPGNGIQLSE GEHRGRLLVP YYCTGTSPKF NAGGALISDD GGRTWRRGKA INEGRTVNGE
VVDEQDVHDD DATTHESVFV ERSDGDVLCL FRNQHHLGRV GKAVSHDGGE TWDTVEFDPM
LPDIFSQPNA VTVPAGERGC ASDRIIFANA SLMRPYRGCG VLRLSEDGGR TWKRNRCFNP
YHYVYQCMSV LPDGAIGLLW ERETAGVYFT RLPLSWFGVE ALESK
//
