ID   A0A087E5P9_9BIFI        Unreviewed;       335 AA.
AC   A0A087E5P9;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Cobalamin synthesis protein, P47K {ECO:0000313|EMBL:KFJ03100.1};
GN   ORFNames=BISU_1031 {ECO:0000313|EMBL:KFJ03100.1};
OS   Bifidobacterium subtile.
OC   Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC   Bifidobacteriaceae; Bifidobacterium.
OX   NCBI_TaxID=77635 {ECO:0000313|EMBL:KFJ03100.1, ECO:0000313|Proteomes:UP000029055};
RN   [1] {ECO:0000313|EMBL:KFJ03100.1, ECO:0000313|Proteomes:UP000029055}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 11597 {ECO:0000313|EMBL:KFJ03100.1,
RC   ECO:0000313|Proteomes:UP000029055};
RA   Ventura M., Milani C., Lugli G.A.;
RT   "Genomics of Bifidobacteria.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFJ03100.1}.
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DR   EMBL; JGZR01000007; KFJ03100.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A087E5P9; -.
DR   STRING; 77635.BISU_1031; -.
DR   eggNOG; COG0523; Bacteria.
DR   Proteomes; UP000029055; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd03112; CobW-like; 1.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR13748; COBW-RELATED; 1.
DR   PANTHER; PTHR13748:SF70; PROTEIN COBW; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029055}.
FT   DOMAIN          221..312
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
SQ   SEQUENCE   335 AA;  36341 MW;  201330137D2CBFF6 CRC64;
     MTGYLGAGKT TLLNHLLRRP GARIGVIIND FGKINVDAAL VTGQVDEAAS ISGGCLCCMP
     DGGGLDDALK SLARPKLRLD AIIIEASGIA DPIALARIIH FSSAPHIRPG GIVELVDAVE
     HFHSVDVSDE PPARYAATNL IVITKTDLLA ESQREAIISR IRQRVRMRNP DAQFVIADRE
     RIDSDLVFDV ASDEDPVDEL PIAQLIRDST PESETHEHHH AHSVSQELTE AVSPSALIEL
     LENPPAGAYR LKGRVAIRER RKANGAAGYV VNLVGRSIHI APMASPARPG ELVAIGMHLD
     VEEARRRFDA LAHTPADQPD PMGLRHVHRY ARLSR
//