ID   A0A087E9R4_9BIFI        Unreviewed;       536 AA.
AC   A0A087E9R4;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Histidine kinase-like protein {ECO:0000313|EMBL:KFJ04515.1};
DE            EC=2.7.13.3 {ECO:0000313|EMBL:KFJ04515.1};
GN   ORFNames=BISU_0522 {ECO:0000313|EMBL:KFJ04515.1};
OS   Bifidobacterium subtile.
OC   Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC   Bifidobacteriaceae; Bifidobacterium.
OX   NCBI_TaxID=77635 {ECO:0000313|EMBL:KFJ04515.1, ECO:0000313|Proteomes:UP000029055};
RN   [1] {ECO:0000313|EMBL:KFJ04515.1, ECO:0000313|Proteomes:UP000029055}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 11597 {ECO:0000313|EMBL:KFJ04515.1,
RC   ECO:0000313|Proteomes:UP000029055};
RA   Ventura M., Milani C., Lugli G.A.;
RT   "Genomics of Bifidobacteria.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFJ04515.1}.
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DR   EMBL; JGZR01000003; KFJ04515.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A087E9R4; -.
DR   STRING; 77635.BISU_0522; -.
DR   eggNOG; COG3920; Bacteria.
DR   Proteomes; UP000029055; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.30.450.280; GAF domain; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR038424; H_kinase_PdtaS_GAF_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR022066; PdtaS_GAF.
DR   InterPro; IPR011495; Sig_transdc_His_kin_sub2_dim/P.
DR   PANTHER; PTHR41523:SF7; ETHYLENE RESPONSE SENSOR PROTEIN; 1.
DR   PANTHER; PTHR41523; TWO-COMPONENT SYSTEM SENSOR PROTEIN; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF07568; HisKA_2; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF12282; PdtaS_GAF; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:KFJ04515.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029055};
KW   Transferase {ECO:0000313|EMBL:KFJ04515.1}.
FT   DOMAIN          324..523
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
SQ   SEQUENCE   536 AA;  59687 MW;  AC26C577F95483B1 CRC64;
     MHAWYIFAHR DLLGNLKHID PLQACALRMM ETMADFTHIL ATRPDFDDSD REWLHHLVAD
     WQVIADLSFA DLLLVLQKGD GSYVVAEQCR PSTVMTLRID DVVGNEIKDD MIDELDTTMR
     SNDVVRSTVL RDVGRSTVCN VYAPVRHNGK TLGVVIRETN MSTRESNGRY ESESINAGKQ
     LFEMIPREQF PYHDPVMNQR HNARVSDGFI LLTVDGVVRY SSPNAISCFR RLGAVTTMQG
     QYLSEIGTQL LHTKDPVPEA LPLVLAGKAA VDSELNANRS VISIRSLPLY GANGRSGALI
     LCRDVTELRR RDQELQTKDA TISEIHHRVK NNLQAVSALL RLQARKTKSD EVKKELAEAQ
     RRVQTIAMVH EGLSQTADEM VDYDKVISNL LKMTVDLATM RDQHIHIDYI GSFGMMPAQD
     ATPLSLVLTE LITNAVEHGF EGRKDGRITI SVGRGGNNLN VVVEDDGSGL DTEEDNGMAR
     SSGSGLGTQI INTFVTNDFG GTVHWEPRRE GGTRVILDMR LRAAQDLQED SNATDL
//