ID   A0A087EFF5_9BIFI        Unreviewed;       519 AA.
AC   A0A087EFF5;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Histidine kinase {ECO:0000313|EMBL:KFJ06506.1};
DE            EC=2.7.13.3 {ECO:0000313|EMBL:KFJ06506.1};
GN   ORFNames=BITS_1187 {ECO:0000313|EMBL:KFJ06506.1};
OS   Bifidobacterium tsurumiense.
OC   Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC   Bifidobacteriaceae; Bifidobacterium.
OX   NCBI_TaxID=356829 {ECO:0000313|EMBL:KFJ06506.1, ECO:0000313|Proteomes:UP000029080};
RN   [1] {ECO:0000313|EMBL:KFJ06506.1, ECO:0000313|Proteomes:UP000029080}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 13495 {ECO:0000313|EMBL:KFJ06506.1,
RC   ECO:0000313|Proteomes:UP000029080};
RA   Ventura M., Milani C., Lugli G.A.;
RT   "Genomics of Bifidobacteria.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFJ06506.1}.
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DR   EMBL; JGZU01000007; KFJ06506.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A087EFF5; -.
DR   STRING; 356829.BITS_1187; -.
DR   eggNOG; COG3920; Bacteria.
DR   Proteomes; UP000029080; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004673; F:protein histidine kinase activity; IEA:UniProtKB-EC.
DR   Gene3D; 3.30.450.280; GAF domain; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR038424; H_kinase_PdtaS_GAF_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR005467; His_kinase_dom.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR022066; PdtaS_GAF.
DR   InterPro; IPR011495; Sig_transdc_His_kin_sub2_dim/P.
DR   PANTHER; PTHR41523:SF7; ETHYLENE RESPONSE SENSOR PROTEIN; 1.
DR   PANTHER; PTHR41523; TWO-COMPONENT SYSTEM SENSOR PROTEIN; 1.
DR   Pfam; PF02518; HATPase_c; 1.
DR   Pfam; PF07568; HisKA_2; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   Pfam; PF12282; PdtaS_GAF; 1.
DR   SMART; SM00387; HATPase_c; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50109; HIS_KIN; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000313|EMBL:KFJ06506.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029080};
KW   Transferase {ECO:0000313|EMBL:KFJ06506.1}.
FT   DOMAIN          314..513
FT                   /note="Histidine kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50109"
SQ   SEQUENCE   519 AA;  57430 MW;  86BDD222EA7E4CA7 CRC64;
     MAPWNVIERH VVAYRTMRMM VGMADFTHIL ASRPDFDDSD REWLHHLVAD WQVIADLSFA
     DLLLILQTGD GGYVVAEQCR PSTVMTLRTE DVVDNAVNDD MVAELDAAML SDDIFRSTVL
     RSVGKSTVCN VYAPIHHNGK TLGLVVRETN MSTRESTGRY ENESIKAGKQ LFEMIPRGEF
     PYKDSVMNQR HIARVADGFI VLSVDGVVQY ASPNAISCFR RLGSLVTMQG QYLSEVGTGL
     LHTNDSFPES LPLVLSGKAA IDSELEANRS VVSMRSLPLF DERGRTGAIV LCRDVTELRR
     REQELQTKDA TISEIHHRVK NNLQAVSALL RLQARKTTSL EVKKGLEEAQ RRVQTIAMVH
     EGLSQTADEI VDFDKVISNL LKMSVDLATM RDQHIHINYI GKFGMMPAQD ATPLSLVLTE
     LITNAVEHGF EGRKDGNITI SVGRGGNNLN VVVEDDGSGL VMEEGRTMPR SAGSGLGTQI
     INTFVTNDFG GTVRWEARRE GGTRVILDMK LRAAASESE
//