ID A0A087GD48_ARAAL Unreviewed; 1257 AA.
AC A0A087GD48;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
GN OrderedLocusNames=AALP_Aa8g430800 {ECO:0000313|EMBL:KFK27800.1};
OS Arabis alpina (Alpine rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis.
OX NCBI_TaxID=50452 {ECO:0000313|EMBL:KFK27800.1, ECO:0000313|Proteomes:UP000029120};
RN [1] {ECO:0000313|Proteomes:UP000029120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pajares {ECO:0000313|Proteomes:UP000029120};
RX PubMed=27246759; DOI=10.1038/nplants.2014.23;
RA Willing E.M., Rawat V., Mandakova T., Maumus F., James G.V.,
RA Nordstroem K.J., Becker C., Warthmann N., Chica C., Szarzynska B.,
RA Zytnicki M., Albani M.C., Kiefer C., Bergonzi S., Castaings L.,
RA Mateos J.L., Berns M.C., Bujdoso N., Piofczyk T., de Lorenzo L.,
RA Barrero-Sicilia C., Mateos I., Piednoel M., Hagmann J., Chen-Min-Tao R.,
RA Iglesias-Fernandez R., Schuster S.C., Alonso-Blanco C., Roudier F.,
RA Carbonero P., Paz-Ares J., Davis S.J., Pecinka A., Quesneville H.,
RA Colot V., Lysak M.A., Weigel D., Coupland G., Schneeberger K.;
RT "Genome expansion of Arabis alpina linked with retrotransposition and
RT reduced symmetric DNA methylation.";
RL Nat. Plants 1:14023-14023(2015).
CC -!- SIMILARITY: Belongs to the peptidase S10 family.
CC {ECO:0000256|ARBA:ARBA00009431}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM002876; KFK27800.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087GD48; -.
DR EnsemblPlants; KFK27800; KFK27800; AALP_AA8G430800.
DR Gramene; KFK27800; KFK27800; AALP_AA8G430800.
DR eggNOG; KOG1075; Eukaryota.
DR eggNOG; KOG1282; Eukaryota.
DR OrthoDB; 693331at2759; -.
DR Proteomes; UP000029120; Chromosome 8.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0004185; F:serine-type carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd06222; RNase_H_like; 1.
DR CDD; cd01650; RT_nLTR_like; 1.
DR Gene3D; 3.40.50.11320; -; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR001563; Peptidase_S10.
DR InterPro; IPR044730; RNase_H-like_dom_plant.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR000477; RT_dom.
DR InterPro; IPR026960; RVT-Znf.
DR PANTHER; PTHR46890; NON-LTR RETROLELEMENT REVERSE TRANSCRIPTASE-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR46890:SF45; RNA BINDING _ RNA-DIRECTED DNA POLYMERASE; 1.
DR Pfam; PF00450; Peptidase_S10; 2.
DR Pfam; PF00078; RVT_1; 1.
DR Pfam; PF13456; RVT_3; 1.
DR Pfam; PF13966; zf-RVT; 1.
DR PRINTS; PR00724; CRBOXYPTASEC.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 2.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000029120};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..1257
FT /note="Reverse transcriptase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001821893"
FT DOMAIN 470..736
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
SQ SEQUENCE 1257 AA; 142978 MW; 0959DF79801D408C CRC64;
MSLTLKLLLL LLVFSHHADS GSIVKFLPGF EGPLPFELET GYIGVGEEEE LQLFYYFIKS
ENNPQEDPLL IWMTGGPGCS SVNGFLYEIG PLTIKIEAYD GNIPSLVPTT YSWTKLANIL
FLDQPVGSGF SYKRTPITDK SSDTLEVVRV HEFLRKWLDK HPEFFSNPFY VAGDSYSGKI
VPALVQKISE ENYRCCKPPI NLQGYVLGNP VTNIVEELNN RIPYAHGMAL ISDELYEAMK
KICKGNYVFG ASRNTECLKL IEKFHKCTDN IHVYNILLSY CDMTSPDCLT YKFLLLSYWA
NDKRVQDALQ VNKGSIEEWV RCSGTILYNK NMNSSLPYHI NNSNQGYRSL IYNKLIRLAR
NRILAIEDED GLIQRGDVAI GNTATTYFTK LFQSTRQPTE DYVQVFDGFQ KRVTDEMNTE
LTRPVTEDEV RHAIFDIGPD RAPGPDGITG AFYQQFWPDI KEEILSEITL IFQRGAFQGP
TNHTNICLIP KPDVPKSMSD FRPIALCNVS YKIISKILVG RLKKVLPGII SNTQAAFIPG
RHIMDNVIIA HEMLHSLKRR KRWAKSYMTV KTDISKAYDR MEWQFIKDTM MQMGFNDTWI
GWIMMCVETV TFSTLVNGVP TGTIIPHRGI RQGDPLSPYI FILCAEVLSH LFTRAAASKQ
LKGMKISHTG PTVNHLLFAD DALFFCHAHQ LSCTTILRLL SEYERVSGQA INLSKSAITF
GAKVRDDIKS RLRHILNIHN DGGCGKYLGL PESIGRKKKE IFQSVLDKVK QRTRSWSHRY
LSEAGREVLL KTVALALPVY TMNCFKLPKG TCAELNTIIA NDWWSKGSDK RSVHWFSWKR
MGLPKKEGGL GFRDIENFNL ALLGKQVHRL FTNPSSLVAQ LLKGRYFPAT NIMEAGNGSK
PSYIWRSLLD GRELVKKGLR CLVGDGANIR AFQDNWLDTH PPRSPRPISD IPTNIQLVKD
LMLRGTNRWN MELLSQTIHA ADVQEILKLP VSSSQLHDLI GWNYTKDGMY TVRSGYWLST
HLPDQIPIPP PSRNQHINEA IWKLQTAPKL RHFCWRIISQ AMPIGSILQR RGIAQSIQCR
RCGDADETPD HLFFGCEYAK QIWEDVGMAW VIRDSHGFYK EAGSGIGTSC TTVLEAELQA
LLMAVIYAWS KGYERIIFEG DNITVYNLVT GEDLQFGLFN RLSEIRHWLN KFREADIRWV
HRESNKTLAN KKSNPGYTRT YANKMTFATV KGGGHTAEYK PNESFIMFQR WISGQPL
//
