ID   A0A087GK54_ARAAL        Unreviewed;       520 AA.
AC   A0A087GK54;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 35.
DE   RecName: Full=Ferulate-5-hydroxylase {ECO:0008006|Google:ProtNLM};
GN   OrderedLocusNames=AALP_Aa7g237600 {ECO:0000313|EMBL:KFK30256.1};
OS   Arabis alpina (Alpine rock-cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis.
OX   NCBI_TaxID=50452 {ECO:0000313|EMBL:KFK30256.1, ECO:0000313|Proteomes:UP000029120};
RN   [1] {ECO:0000313|Proteomes:UP000029120}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Pajares {ECO:0000313|Proteomes:UP000029120};
RX   PubMed=27246759; DOI=10.1038/nplants.2014.23;
RA   Willing E.M., Rawat V., Mandakova T., Maumus F., James G.V.,
RA   Nordstroem K.J., Becker C., Warthmann N., Chica C., Szarzynska B.,
RA   Zytnicki M., Albani M.C., Kiefer C., Bergonzi S., Castaings L.,
RA   Mateos J.L., Berns M.C., Bujdoso N., Piofczyk T., de Lorenzo L.,
RA   Barrero-Sicilia C., Mateos I., Piednoel M., Hagmann J., Chen-Min-Tao R.,
RA   Iglesias-Fernandez R., Schuster S.C., Alonso-Blanco C., Roudier F.,
RA   Carbonero P., Paz-Ares J., Davis S.J., Pecinka A., Quesneville H.,
RA   Colot V., Lysak M.A., Weigel D., Coupland G., Schneeberger K.;
RT   "Genome expansion of Arabis alpina linked with retrotransposition and
RT   reduced symmetric DNA methylation.";
RL   Nat. Plants 1:14023-14023(2015).
CC   -!- SIMILARITY: Belongs to the cytochrome P450 family.
CC       {ECO:0000256|RuleBase:RU000461}.
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DR   EMBL; CM002875; KFK30256.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A087GK54; -.
DR   EnsemblPlants; KFK30256; KFK30256; AALP_AA7G237600.
DR   Gramene; KFK30256; KFK30256; AALP_AA7G237600.
DR   eggNOG; KOG0156; Eukaryota.
DR   OMA; LPCLDDQ; -.
DR   OrthoDB; 368727at2759; -.
DR   Proteomes; UP000029120; Chromosome 7.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro.
DR   GO; GO:0009809; P:lignin biosynthetic process; IEA:EnsemblPlants.
DR   GO; GO:0010224; P:response to UV-B; IEA:EnsemblPlants.
DR   CDD; cd11072; CYP71-like; 1.
DR   Gene3D; 1.10.630.10; Cytochrome P450; 1.
DR   InterPro; IPR001128; Cyt_P450.
DR   InterPro; IPR017972; Cyt_P450_CS.
DR   InterPro; IPR002401; Cyt_P450_E_grp-I.
DR   InterPro; IPR036396; Cyt_P450_sf.
DR   PANTHER; PTHR47945; CYTOCHROME P450 84A1-RELATED; 1.
DR   PANTHER; PTHR47945:SF5; CYTOCHROME P450 84A1-RELATED; 1.
DR   Pfam; PF00067; p450; 1.
DR   PRINTS; PR00463; EP450I.
DR   PRINTS; PR00385; P450.
DR   SUPFAM; SSF48264; Cytochrome P450; 1.
DR   PROSITE; PS00086; CYTOCHROME_P450; 1.
PE   3: Inferred from homology;
KW   Heme {ECO:0000256|RuleBase:RU000461}; Iron {ECO:0000256|RuleBase:RU000461};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Metal-binding {ECO:0000256|RuleBase:RU000461};
KW   Monooxygenase {ECO:0000256|RuleBase:RU000461};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000461};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029120};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   520 AA;  58655 MW;  01FC30EEA96C4E4D CRC64;
     MEFSISQTLS KVLDPTTAVL IVVSLFIFIG LISRRRRLPY PPGPGGWPII GNMLMMDQLT
     HRGLASLAKK YGGLCHLRMG FLHMFAVSSP EVAKQVLQVQ DSIFSNRPAT IAISYLTYDR
     ADMAFAHYGP FWRQMRKVCV MKVFSRKRAE SWASVRDEVD KMVRSVSSNV GKPINVGEQI
     FALTRNITYR AAFGSACITG QDEFIRILQE FSKLFGAFNV ADFIPYFGWI DPQGINKRLV
     KARNDLDGFI DEIIDEHMKK KEDQNTVDDG DIVDTDMVDD LLTFYSEEAK LVSEATDLQN
     SIKLTRDNIK AIIMDVMFGG TETVASAIEW ALTELLRSPE DLKRVQQELA DVVGLDRRVE
     ESDIEKLTFL KCTLKETLRL HPPIPLLLHE TSEDAEIDGY YVPKRSRIMI NAFAIGRDPK
     SWVDPDTFRP ARFLEPGVPD FKGSNFEFIP FGSGRRSCPG MQLGLYALDL AVAHILHCFT
     WELPDGMKPN DLDMSDVFGL TAPKATRLFA VPITRLTCDV
//