ID A0A087GKW6_ARAAL Unreviewed; 475 AA.
AC A0A087GKW6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=USP domain-containing protein {ECO:0000259|PROSITE:PS50235};
GN OrderedLocusNames=AALP_Aa7g272700 {ECO:0000313|EMBL:KFK30518.1};
OS Arabis alpina (Alpine rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis.
OX NCBI_TaxID=50452 {ECO:0000313|EMBL:KFK30518.1, ECO:0000313|Proteomes:UP000029120};
RN [1] {ECO:0000313|Proteomes:UP000029120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pajares {ECO:0000313|Proteomes:UP000029120};
RX PubMed=27246759; DOI=10.1038/nplants.2014.23;
RA Willing E.M., Rawat V., Mandakova T., Maumus F., James G.V.,
RA Nordstroem K.J., Becker C., Warthmann N., Chica C., Szarzynska B.,
RA Zytnicki M., Albani M.C., Kiefer C., Bergonzi S., Castaings L.,
RA Mateos J.L., Berns M.C., Bujdoso N., Piofczyk T., de Lorenzo L.,
RA Barrero-Sicilia C., Mateos I., Piednoel M., Hagmann J., Chen-Min-Tao R.,
RA Iglesias-Fernandez R., Schuster S.C., Alonso-Blanco C., Roudier F.,
RA Carbonero P., Paz-Ares J., Davis S.J., Pecinka A., Quesneville H.,
RA Colot V., Lysak M.A., Weigel D., Coupland G., Schneeberger K.;
RT "Genome expansion of Arabis alpina linked with retrotransposition and
RT reduced symmetric DNA methylation.";
RL Nat. Plants 1:14023-14023(2015).
CC -!- SIMILARITY: Belongs to the peptidase C19 family.
CC {ECO:0000256|ARBA:ARBA00009085}.
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DR EMBL; CM002875; KFK30518.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087GKW6; -.
DR EnsemblPlants; KFK30518; KFK30518; AALP_AA7G272700.
DR Gramene; KFK30518; KFK30518; AALP_AA7G272700.
DR eggNOG; KOG1868; Eukaryota.
DR OMA; CEREGND; -.
DR OrthoDB; 1204714at2759; -.
DR Proteomes; UP000029120; Chromosome 7.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR CDD; cd02662; Peptidase_C19F; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR24006:SF888; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR Pfam; PF00443; UCH; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00972; USP_1; 1.
DR PROSITE; PS50235; USP_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029120};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 18..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 60..475
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
SQ SEQUENCE 475 AA; 53650 MW; 26FA3BE1FC3955E7 CRC64;
MMQAIISTLT ERFKLSNWVS HLSLASILGV AGFVYALKDN RFRNLNLFST KEEDDSIFVP
GLQNLGNNCF LNVILQALAS CKDFRSFLQW VIEDAKEEEQ FPLSFALSSL LEELCIVGRR
RSVSSPREVM LELTDYVRNF NLTSQQDAAE ALLHLISSLQ EEIVHCYRPS ESSNLSDIVF
SRNLRILAPS EGVHGLMELK RWHKHLRGPF DGILGSTLMC RTCSSQISLE FQFFHTLPLS
PLLDIGGSNI MFGCTLENCL KKFLDAEKVE NYFCKKCWHG AALKFLSVIR ASETDIEKLR
SCTGEDLCDC KTSLCLERMP WSNSYSYILK QLIIARFPKL LCIQVQRASL NMYGDSVKLS
GHIAFPLVLD LSLYTPSSIG LNIEKTQLSS QYQNPEASSS DRGMYRLVTV VEHFGRTGSG
HYTVYRSVKV ASQMEEEDDH CDDLSWFSIS DSEVSRVSES DVLGAEASLL FYEKA
//
