ID A0A087GVX1_ARAAL Unreviewed; 812 AA.
AC A0A087GVX1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN OrderedLocusNames=AALP_Aa5g091900 {ECO:0000313|EMBL:KFK34023.1};
OS Arabis alpina (Alpine rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis.
OX NCBI_TaxID=50452 {ECO:0000313|EMBL:KFK34023.1, ECO:0000313|Proteomes:UP000029120};
RN [1] {ECO:0000313|Proteomes:UP000029120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pajares {ECO:0000313|Proteomes:UP000029120};
RX PubMed=27246759; DOI=10.1038/nplants.2014.23;
RA Willing E.M., Rawat V., Mandakova T., Maumus F., James G.V.,
RA Nordstroem K.J., Becker C., Warthmann N., Chica C., Szarzynska B.,
RA Zytnicki M., Albani M.C., Kiefer C., Bergonzi S., Castaings L.,
RA Mateos J.L., Berns M.C., Bujdoso N., Piofczyk T., de Lorenzo L.,
RA Barrero-Sicilia C., Mateos I., Piednoel M., Hagmann J., Chen-Min-Tao R.,
RA Iglesias-Fernandez R., Schuster S.C., Alonso-Blanco C., Roudier F.,
RA Carbonero P., Paz-Ares J., Davis S.J., Pecinka A., Quesneville H.,
RA Colot V., Lysak M.A., Weigel D., Coupland G., Schneeberger K.;
RT "Genome expansion of Arabis alpina linked with retrotransposition and
RT reduced symmetric DNA methylation.";
RL Nat. Plants 1:14023-14023(2015).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: In the C-terminal section; belongs to the peptidase M41
CC family. {ECO:0000256|ARBA:ARBA00010044}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the AAA ATPase
CC family. {ECO:0000256|ARBA:ARBA00010550}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM002873; KFK34023.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087GVX1; -.
DR MEROPS; M41.A04; -.
DR EnsemblPlants; KFK34023; KFK34023; AALP_AA5G091900.
DR Gramene; KFK34023; KFK34023; AALP_AA5G091900.
DR eggNOG; KOG0731; Eukaryota.
DR OMA; QKWLRMV; -.
DR OrthoDB; 117at2759; -.
DR Proteomes; UP000029120; Chromosome 5.
DR GO; GO:0009507; C:chloroplast; IEA:EnsemblPlants.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd19501; RecA-like_FtsH; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.720.210; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.58.760; Peptidase M41; 1.
DR HAMAP; MF_01458; FtsH; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR005936; FtsH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011546; Pept_M41_FtsH_extracell.
DR InterPro; IPR000642; Peptidase_M41.
DR InterPro; IPR037219; Peptidase_M41-like.
DR NCBIfam; TIGR01241; FtsH_fam; 1.
DR PANTHER; PTHR23076:SF135; ATP-DEPENDENT ZINC METALLOPROTEASE FTSH 7, CHLOROPLASTIC; 1.
DR PANTHER; PTHR23076; METALLOPROTEASE M41 FTSH; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF06480; FtsH_ext; 1.
DR Pfam; PF01434; Peptidase_M41; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF140990; FtsH protease domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000029120};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 280..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 367..507
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 92..127
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 812 AA; 88794 MW; 96F6CCA3420437A3 CRC64;
MTTTFEFTRP GIHDRFGFAT CCSNSSLLYN SHTSSSFFSD RFRVFRYNPN RFISNSIPLL
LQKKPFTVLR NDKRFNLCDG FSTKKRGVEE RRRTVVNCQE DDQKGSSSSE EEGAQDSSSK
RKRDKQEKDK VWWSKGKKWE WEPIIQAQGI SVLLLQLGVV MFMMRLLRPG IPLPGSEPRT
QTTFVSVPYS EFLSKVNSNQ VQKVEVDGVQ VLFKLKDDGK WQESETSRLP ESSESLLRVV
APTKRVVYST TRPGDIKTPY EKMLGNNVEF GSPDKRSGGF FNSGFIALFY IAVLAGLIRF
PFGVSMNVTS QLRTRKSGGS DGGKASGGSE TITFADVAGV DEAKEELEEI VEFLRNPDKY
VRLGARPPRG VLLVGLPGTG KTLLAKAVAG EADVPFISCS ASEFVELYVG MGASRVRDLF
ARAKKEAPSI IFIDEIDAVA KSRDGKFRLA SNDEREQTLN QLLTEMDGFD SNSAVIVLGA
TNRADVLDPA LRRPGRFDRV VSVETPDKIG RESILRVHVT KKELPLGDDV NLSSIALMTT
GFTGADLANL VNEAALLAGR KNKTTVDKID FIDAVERSIA GIEKKTARLK GSEKGVVARH
EAGHAVVGTA VAKLLTGQPR VEKLSILPRS GGALGFTYIP PSSEDRYLLF IDELLGRLVT
LLGGRAAEEV VYSGRVSTGA FDDIRRATDM AYKAVAEYGL NQKIGPVSVA TLSGGGIDDS
GASPWGRDQG KLVDLVQREV TNLLQSALDV ALSVVRANPD VLEGLGAQLE EKEKVEGEEL
QKWLNMVVAP EELAVFVKGK QVALLPAQAS SS
//
