ID A0A087HRP6_ARAAL Unreviewed; 971 AA.
AC A0A087HRP6;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN OrderedLocusNames=AALP_Aa1g304700 {ECO:0000313|EMBL:KFK44798.1};
OS Arabis alpina (Alpine rock-cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis.
OX NCBI_TaxID=50452 {ECO:0000313|EMBL:KFK44798.1, ECO:0000313|Proteomes:UP000029120};
RN [1] {ECO:0000313|Proteomes:UP000029120}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Pajares {ECO:0000313|Proteomes:UP000029120};
RX PubMed=27246759; DOI=10.1038/nplants.2014.23;
RA Willing E.M., Rawat V., Mandakova T., Maumus F., James G.V.,
RA Nordstroem K.J., Becker C., Warthmann N., Chica C., Szarzynska B.,
RA Zytnicki M., Albani M.C., Kiefer C., Bergonzi S., Castaings L.,
RA Mateos J.L., Berns M.C., Bujdoso N., Piofczyk T., de Lorenzo L.,
RA Barrero-Sicilia C., Mateos I., Piednoel M., Hagmann J., Chen-Min-Tao R.,
RA Iglesias-Fernandez R., Schuster S.C., Alonso-Blanco C., Roudier F.,
RA Carbonero P., Paz-Ares J., Davis S.J., Pecinka A., Quesneville H.,
RA Colot V., Lysak M.A., Weigel D., Coupland G., Schneeberger K.;
RT "Genome expansion of Arabis alpina linked with retrotransposition and
RT reduced symmetric DNA methylation.";
RL Nat. Plants 1:14023-14023(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; CM002869; KFK44798.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087HRP6; -.
DR EnsemblPlants; KFK44798; KFK44798; AALP_AA1G304700.
DR Gramene; KFK44798; KFK44798; AALP_AA1G304700.
DR eggNOG; ENOG502QTAM; Eukaryota.
DR OMA; PINCKKY; -.
DR OrthoDB; 163787at2759; -.
DR Proteomes; UP000029120; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 2.60.120.430; Galactose-binding lectin; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR021720; Malectin_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48006; LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0281931-RELATED; 1.
DR PANTHER; PTHR48006:SF66; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 4.
DR Pfam; PF11721; Malectin; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000029120};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..971
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001823734"
FT TRANSMEM 625..645
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 681..954
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 709
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 971 AA; 107668 MW; 5350F052BE0CD58F CRC64;
MSIVFLKFLL FFTITSYLAT LTTSVTSPSL HPDELNALKV IATALGIKRL NLSYGDPCIL
KTLKITHKIG FVLNSDSNNT VLCDCSFNNN TICHITEIFL KTMSLPGKLP PQLAKLRHLR
SIDLCRNYLS GTIPMEWASM QYLTFISLCA NNLSGTLPIG LQNFKNLTFL GLEANQFSGQ
IPDELGNLTN LIGLELASNQ FTGRLPSTLA RLVNLERVRI CDNNFTGIIP GYIGNWSRLE
KLHLYASGLK GPIPDAVARL VNLTELSISD TTGINSFPNI SSNVIKHLIL RNVNLSGPIP
SDIWNLTSLK TLDLSFNNLT GEVQGGQKTP TFTYLTGNML SGYIESGALL SSIPNIDLSY
NSFSWSPSCQ EKSNINTYNS SYMKKNLTGL LPCAGPINCK KYQRSLHINC GGESETITNS
WGKITYQADI SQTDAATNHV LENWGISNTG SFTDDASDHD MYFVSTAPGD LSDLDKNTRR
SGDSPNLYKI ARRSALSLTY YAFCLENGLY NVTLHFMEIQ FSEKELYHRV GRRIFDVYVQ
GVLFLKDFNI KEEANGTLTP LVKTKKAVNV TNHTLEIRLY WAGKGTTLIP QRGNYGPLIS
AISLCHSLEP RCGAEKIKQH TNYPLILGAT GALITIILLA LGIYAQKRCR GDKNTRERDL
RAQGLQTCFT WRQLQSATNN FDQANKLGEG GFGSVFKGEL SDGTIIAVKQ LSSKSCQGNR
EFVNEIGMIS GLNHTNLVKL YGCCVEKNQL LLVYEYMENN SLALALYGKS SPKLDWAARQ
KICVGIARGL EFLHEGSMIR MVHRDIKTTN VLLDADLNAK ISDFGLARLH EEEHTHISTK
IAGTIGYMAP EYALWGQLTE KADVYSFGVV AMEIVSGRSN TKQKGSADHV SLINWALTLQ
QTGDIMEIVD TTLEGDFNSK ESVRMIKVAF ICTNSSPSLR PTMSEVMQML EGEIEITQLE
HLKAEGQWYK W
//
