GenomeNet

Database: UniProt
Entry: A0A087MGZ4_9GAMM
LinkDB: A0A087MGZ4_9GAMM
Original site: A0A087MGZ4_9GAMM 
ID   A0A087MGZ4_9GAMM        Unreviewed;       441 AA.
AC   A0A087MGZ4;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   13-FEB-2019, entry version 34.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:KFL36147.1};
GN   ORFNames=N788_04475 {ECO:0000313|EMBL:KFL36147.1};
OS   Arenimonas donghaensis DSM 18148 = HO3-R19.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Arenimonas.
OX   NCBI_TaxID=1121014 {ECO:0000313|EMBL:KFL36147.1, ECO:0000313|Proteomes:UP000029085};
RN   [1] {ECO:0000313|Proteomes:UP000029085}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HO3-R19 {ECO:0000313|Proteomes:UP000029085};
RA   Chen F., Wang G.;
RT   "Genome sequencing of Arenimonas donghaensis.";
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KFL36147.1, ECO:0000313|Proteomes:UP000029085}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HO3-R19 {ECO:0000313|EMBL:KFL36147.1,
RC   ECO:0000313|Proteomes:UP000029085};
RX   PubMed=26380644; DOI=10.1186/s40793-015-0055-4;
RA   Chen F., Wang H., Cao Y., Li X., Wang G.;
RT   "High quality draft genomic sequence of Arenimonas donghaensis DSM
RT   18148(T).";
RL   Stand. Genomic Sci. 10:59-59(2015).
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KFL36147.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AVCJ01000023; KFL36147.1; -; Genomic_DNA.
DR   RefSeq; WP_034224081.1; NZ_AVCJ01000023.1.
DR   EnsemblBacteria; KFL36147; KFL36147; N788_04475.
DR   PATRIC; fig|1121014.3.peg.1781; -.
DR   OrthoDB; 219876at2; -.
DR   Proteomes; UP000029085; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000029085};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      138    269       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      349    418       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     146    153       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      300    320       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   441 AA;  49650 MW;  EF3A7600F5846E34 CRC64;
     MDAAWPRCLE RLEAELPAEE VHTWLRPLQV ETNADGLTLY APNEFVVDQV REHYLARIRE
     LVAHFAGAPA AVALAVGSLK RAVASPVPAP LASPGRAAGP EFAGNVDAHY TFENFVEGRS
     NQLGRAAALQ VAQNPGKAYN PLLLYGGSGL GKTHLMYAAG NFMRRNNPGM RVLYLRSEQF
     FSAMMKSLQD KSMDQFKRQF QQVDALLIDD IQFFAGKNTT QEEFFHTFNA LFDGKQQIIL
     TCDRYPREVE NLETRLKTRL TWGLSVAIEP PDFETRAAIL TAKAAERSVP LPEDVAYLIA
     KRMRSNVRDL EGALNTLAAR SNFMARPITV EFAQETLRDL LRAQQQAVSI SNIQKTVADY
     YQLRMADLLS KRRTRSLARP RQMAMALSKE LTEHSLPEIG DAFGGRDHTT VMHACKVMRE
     LREIDGKLRE DWDKLLRKLS E
//
DBGET integrated database retrieval system