ID   A0A087MLC9_9GAMM        Unreviewed;       298 AA.
AC   A0A087MLC9;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Hydroxymethylglutaryl-CoA lyase {ECO:0000313|EMBL:KFL37682.1};
DE            EC=4.1.3.4 {ECO:0000313|EMBL:KFL37682.1};
GN   ORFNames=N788_00505 {ECO:0000313|EMBL:KFL37682.1};
OS   Arenimonas donghaensis DSM 18148 = HO3-R19.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Arenimonas.
OX   NCBI_TaxID=1121014 {ECO:0000313|EMBL:KFL37682.1, ECO:0000313|Proteomes:UP000029085};
RN   [1] {ECO:0000313|Proteomes:UP000029085}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HO3-R19 {ECO:0000313|Proteomes:UP000029085};
RA   Chen F., Wang G.;
RT   "Genome sequencing of Arenimonas donghaensis.";
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:KFL37682.1, ECO:0000313|Proteomes:UP000029085}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HO3-R19 {ECO:0000313|EMBL:KFL37682.1,
RC   ECO:0000313|Proteomes:UP000029085};
RX   PubMed=26380644; DOI=10.1186/s40793-015-0055-4;
RA   Chen F., Wang H., Cao Y., Li X., Wang G.;
RT   "High quality draft genomic sequence of Arenimonas donghaensis DSM
RT   18148(T).";
RL   Stand. Genomic Sci. 10:59-59(2015).
CC   -!- SIMILARITY: Belongs to the HMG-CoA lyase family.
CC       {ECO:0000256|ARBA:ARBA00009405}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFL37682.1}.
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DR   EMBL; AVCJ01000001; KFL37682.1; -; Genomic_DNA.
DR   RefSeq; WP_034219914.1; NZ_AVCJ01000001.1.
DR   AlphaFoldDB; A0A087MLC9; -.
DR   STRING; 1121014.N788_00505; -.
DR   PATRIC; fig|1121014.3.peg.98; -.
DR   OrthoDB; 9784013at2; -.
DR   Proteomes; UP000029085; Unassembled WGS sequence.
DR   GO; GO:0004419; F:hydroxymethylglutaryl-CoA lyase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd07938; DRE_TIM_HMGL; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR043594; HMGL.
DR   InterPro; IPR000891; PYR_CT.
DR   PANTHER; PTHR42738; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR   PANTHER; PTHR42738:SF7; HYDROXYMETHYLGLUTARYL-COA LYASE; 1.
DR   Pfam; PF00682; HMGL-like; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
DR   PROSITE; PS50991; PYR_CT; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:KFL37682.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029085}.
FT   DOMAIN          7..274
FT                   /note="Pyruvate carboxyltransferase"
FT                   /evidence="ECO:0000259|PROSITE:PS50991"
SQ   SEQUENCE   298 AA;  31080 MW;  BD5AD68C3B669B01 CRC64;
     MSAPAEVRIV EVGPRDGLQN EKTLVPTADK IELVDRLSAT GLRCIEATSF VSPKWVPQMA
     DAAEVFAGIT QRPGVAYPVL VPNLQGYERA REVGASEVAV FSAASEAFNR KNINASIDES
     IERFLPVLER ARADGVKVRG YVSTVLGCPY QGEVPLADVV RVARRLHEAG CYEVSLGDTI
     GIGTPGKARA MLRAVAAEVP MAALAVHFHD TRGQALANIL ACLEDGVGVV DAAVSGTGGC
     PYAPGASGNV ATEDVVYMLE GLGVATGVDL AKLVETGRWL AGKLGRSSGS KVTLAAPL
//