ID A0A087QI78_APTFO Unreviewed; 557 AA.
AC A0A087QI78;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Netrin-1 {ECO:0000256|ARBA:ARBA00015919};
DE Flags: Fragment;
GN ORFNames=AS27_07050 {ECO:0000313|EMBL:KFM00932.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM00932.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM00932.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM00932.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL225618; KFM00932.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087QI78; -.
DR STRING; 9233.A0A087QI78; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR CDD; cd00055; EGF_Lam; 3.
DR CDD; cd03579; NTR_netrin-1_like; 1.
DR Gene3D; 2.40.50.120; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR001134; Netrin_domain.
DR InterPro; IPR018933; Netrin_module_non-TIMP.
DR InterPro; IPR008993; TIMP-like_OB-fold.
DR PANTHER; PTHR10574:SF443; -; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00053; Laminin_EGF; 3.
DR Pfam; PF00055; Laminin_N; 1.
DR Pfam; PF01759; NTR; 1.
DR SMART; SM00643; C345C; 1.
DR SMART; SM00180; EGF_Lam; 3.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF50242; TIMP-like; 1.
DR PROSITE; PS01248; EGF_LAM_1; 1.
DR PROSITE; PS50027; EGF_LAM_2; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
DR PROSITE; PS50189; NTR; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 17..243
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 363..412
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 425..554
FT /note="NTR"
FT /evidence="ECO:0000259|PROSITE:PS50189"
FT REGION 37..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 363..375
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 365..382
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 384..393
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 396..410
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFM00932.1"
FT NON_TER 557
FT /evidence="ECO:0000313|EMBL:KFM00932.1"
SQ SEQUENCE 557 AA; 62468 MW; 7C7B5F93F86D453C CRC64;
FVAQQTPPDP CYDESGAPRR CIPEFVNAAF GKEVQASSTC GKPPTRHCNA SDPRRAHPPA
YLTDLNTASN MTCWRSETLH HSPQNVTLTL SLGKKFEVVY VSLQFCSPRP ESTAILKSMD
YGKTWVPYQY YSSQCRKIYG KPSKATVTKQ NEQEALCTDG LTDLYPLTGG LIAFSTLDGR
PSAQDFDSSP VLQDWVTATD IRVVFSRPHL FRDLGGRDGG EEEGGTGSTP YYYAVGELQV
GGRCKCNGHA ARCVKDKEQK LVCDCKHNTE GPECDRCKPF HYDRPWQRAS AREANECLAC
NCNLHARRCR FNMELYKLSG RKSGGVCLNC RHNTAGRHCH YCKEGFYRDL SKSITDRKAC
KACDCHPVGA AGKTCNQTTG QCPCKDGVTG LTCNRCAKGY QQSRSPVAPC ITPQCSTLCS
SSADCDSYCK PAKGNYKINM KKYCKKDYVV QVNILEMETV ANWAKFTINI LSVYKCRDER
VKRGDNFLWI HLKDLSCKCP KIQISKKYLV MGISENSTDR PGLMADKNSL VIQWRDAWTR
RLRKLQRREK KGKCVKP
//
