ID A0A087QJ80_APTFO Unreviewed; 685 AA.
AC A0A087QJ80;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=histone acetyltransferase {ECO:0000256|ARBA:ARBA00013184};
DE EC=2.3.1.48 {ECO:0000256|ARBA:ARBA00013184};
DE Flags: Fragment;
GN ORFNames=AS27_11223 {ECO:0000313|EMBL:KFM01284.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM01284.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM01284.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM01284.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000256|ARBA:ARBA00004300}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the acetyltransferase family. GCN5 subfamily.
CC {ECO:0000256|ARBA:ARBA00008607}.
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DR EMBL; KL225650; KFM01284.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087QJ80; -.
DR STRING; 9233.A0A087QJ80; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0005813; C:centrosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0004402; F:histone acetyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd05509; Bromo_gcn5_like; 1.
DR Gene3D; 3.40.630.30; -; 2.
DR Gene3D; 1.20.920.10; Bromodomain-like; 1.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR018359; Bromodomain_CS.
DR InterPro; IPR037800; GCN5.
DR InterPro; IPR000182; GNAT_dom.
DR InterPro; IPR009464; PCAF_N.
DR PANTHER; PTHR45750; GH11602P; 1.
DR PANTHER; PTHR45750:SF1; HISTONE ACETYLTRANSFERASE KAT2A; 1.
DR Pfam; PF00583; Acetyltransf_1; 1.
DR Pfam; PF00439; Bromodomain; 1.
DR Pfam; PF06466; PCAF_N; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR SMART; SM00297; BROMO; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
DR SUPFAM; SSF47370; Bromodomain; 1.
DR PROSITE; PS00633; BROMODOMAIN_1; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 1.
DR PROSITE; PS51186; GNAT; 1.
PE 3: Inferred from homology;
KW Bromodomain {ECO:0000256|ARBA:ARBA00023117, ECO:0000256|PROSITE-
KW ProRule:PRU00035}; Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Transferase {ECO:0000313|EMBL:KFM01284.1}.
FT DOMAIN 349..504
FT /note="N-acetyltransferase"
FT /evidence="ECO:0000259|PROSITE:PS51186"
FT DOMAIN 593..663
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFM01284.1"
FT NON_TER 685
FT /evidence="ECO:0000313|EMBL:KFM01284.1"
SQ SEQUENCE 685 AA; 78895 MW; 959C09177DF9F1CB CRC64;
QANDACKCNG WKNPNPPTAP RMDLQQPVTN LSEPCRSCGH ALADHVSHLE NVSEEEINRL
LGMVVDVENL FMSVHKEEDT DTKQVYFYLF KLLRKCILQM SQPVVEGSLG SPPFEKPNIE
QGVLNFVQYK FSHLPPKERQ TMYELSKMFL LCLNYWKLET PSQFRQRSQN DDVATYKVNY
TRWLCYCHVP QSCDSLPRYE TTHVFGRSLL KSIFTVTRRQ LLEKFRVEKD KLVPEKRTLI
LTHFPKFLSM LEEEIYGENS PIWEADFTVP ATEGAQLVSR PEPLPGRAGV SPTLGELGPS
LVPPGAGCAA LLHAPGEKRK LPESLTLEDA KRIRVMGDIP MELVNEVMLT ITDPAAMLGP
ETSLLSANAA RDETARLEER RGIIEFHVIG NSLSQKSNKK ILMWLVGLQN VFSHQLPRMP
KEYITRLVFD PCVARGGYGT HLMNHLKEYH IKHNILYFLT YADEYAIGYF KKQGFSKDIK
VPKSRYLGYI KDYEGATLME CELNPRIPYT ELSHIIKKQK EIIKKLIERK QAQIRKVYPG
LTCFKEGVRQ IPIESVPGIR ETGWKPLGKE KGKELKDPDQ LYNTLKNLLA QIKTHPSAWP
FMEPVKKSEA PDYYEIIRFP IDLKTMTERL KNRYYVTKKL FIADLQRIIT NCREYNPPDS
DYCKCANTLE KFFYFKLKEG GLIDK
//
