ID A0A087QL65_APTFO Unreviewed; 772 AA.
AC A0A087QL65;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=GDH/6PGL endoplasmic bifunctional protein {ECO:0000313|EMBL:KFM01969.1};
DE Flags: Fragment;
GN ORFNames=AS27_13015 {ECO:0000313|EMBL:KFM01969.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM01969.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM01969.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM01969.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway.
CC {ECO:0000256|ARBA:ARBA00004959}.
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DR EMBL; KL225737; KFM01969.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087QL65; -.
DR STRING; 9233.A0A087QL65; -.
DR UniPathway; UPA00115; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0017057; F:6-phosphogluconolactonase activity; IEA:InterPro.
DR GO; GO:0004345; F:glucose-6-phosphate dehydrogenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR CDD; cd01400; 6PGL; 1.
DR Gene3D; 3.40.50.1360; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR005900; 6-phosphogluconolactonase_DevB.
DR InterPro; IPR001282; G6P_DH.
DR InterPro; IPR019796; G6P_DH_AS.
DR InterPro; IPR022675; G6P_DH_C.
DR InterPro; IPR022674; G6P_DH_NAD-bd.
DR InterPro; IPR006148; Glc/Gal-6P_isomerase.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR NCBIfam; TIGR01198; pgl; 1.
DR PANTHER; PTHR23429:SF7; GDH_6PGL ENDOPLASMIC BIFUNCTIONAL PROTEIN; 1.
DR PANTHER; PTHR23429; GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD; 1.
DR Pfam; PF02781; G6PD_C; 1.
DR Pfam; PF00479; G6PD_N; 1.
DR Pfam; PF01182; Glucosamine_iso; 1.
DR PRINTS; PR00079; G6PDHDRGNASE.
DR SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
DR PROSITE; PS00069; G6P_DEHYDROGENASE; 1.
PE 4: Predicted;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00022526};
KW Glucose metabolism {ECO:0000256|ARBA:ARBA00022526};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286}.
FT DOMAIN 11..193
FT /note="Glucose-6-phosphate dehydrogenase NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF00479"
FT DOMAIN 199..489
FT /note="Glucose-6-phosphate dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02781"
FT DOMAIN 541..763
FT /note="Glucosamine/galactosamine-6-phosphate isomerase"
FT /evidence="ECO:0000259|Pfam:PF01182"
FT BINDING 190
FT /ligand="substrate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10005"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFM01969.1"
FT NON_TER 772
FT /evidence="ECO:0000313|EMBL:KFM01969.1"
SQ SEQUENCE 772 AA; 87220 MW; EE2D4E2D607D1CFB CRC64;
AEVSQGHISV VLLGATGDLA KKYLWQGLFQ LYMDQVSSGH SFTFHGAALT ALEPGQRLMF
DVLKKLACPP DESPNRCAVL KDQFLKLSQY HQLKTAENYT VLNREIETLL RQEGLKEAGR
IFYFSVPPFA YTEIARHINS SCRPPPGAWL RVVLEKPFGH DLESAQQLAA ELTSFFREEE
MYRVDHYLGK QAVAHILPFR DHNRQFLDPI WNRHHVERVE IVLKETVDAK GRTSFYEQYG
VIRDVLQNHL TEALMFLTME LPANVSSAEE VLQRKLQAFQ FLRGLEKNSV VLGQYQAYAS
QVQEELQKAQ DYISTTPTFA GVLIHSDSLR WEGVPFLLTS GKALDERVGY VRVLFKNQAY
CTQSETLRDA GHSQCKAKQI IFYIGHGALK TPAVLVSRNL FRPVMPEGSW REAVGQSDLH
IFGQPLSDYY VYSPVKERDA YSVLISNIYH GRKDFFITTE NLLASWGFWT PLLDSISHQP
LRLYPGGVEN QDLLDFEMVS GEVAFTLAEP VELLNPNGLM PSEYRTIQSK FRQSPLVSAW
SEDLISQLAS DIEKTASRTV AHSGQFHLAL SGGSSPVVLF QQLARHHYAF PWKHTHIWLV
DERCVPLSDT ESNFFSLHNH LLQNVRVPYF NVHPMPVHLN QRLCVEEDRG TELYAKEIMA
LVANASFDLV LLGVGTDGHT ASLFPQSENG LEGAQTVVLT ESPVKPHQRM SLSLPVINKA
RQVFVLVLGK GKHNITTLLS RVGHEPRKWP ISGVSPSSGQ LVWYVDYEAL LG
//
