ID   A0A087QMJ3_APTFO        Unreviewed;       489 AA.
AC   A0A087QMJ3;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Podocalyxin {ECO:0000256|ARBA:ARBA00017371};
DE   AltName: Full=Podocalyxin-like protein 1 {ECO:0000256|ARBA:ARBA00031141};
DE   Flags: Fragment;
GN   ORFNames=AS27_03788 {ECO:0000313|EMBL:KFM02447.1};
OS   Aptenodytes forsteri (Emperor penguin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC   Aptenodytes.
OX   NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM02447.1, ECO:0000313|Proteomes:UP000053286};
RN   [1] {ECO:0000313|EMBL:KFM02447.1, ECO:0000313|Proteomes:UP000053286}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM02447.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Apical cell membrane
CC       {ECO:0000256|ARBA:ARBA00004221}. Cell membrane
CC       {ECO:0000256|ARBA:ARBA00004236}. Cell projection, filopodium
CC       {ECO:0000256|ARBA:ARBA00004486}. Cell projection, lamellipodium
CC       {ECO:0000256|ARBA:ARBA00004510}. Cell projection, microvillus
CC       {ECO:0000256|ARBA:ARBA00004105}. Cell projection, ruffle
CC       {ECO:0000256|ARBA:ARBA00004466}. Membrane raft
CC       {ECO:0000256|ARBA:ARBA00004285}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC       {ECO:0000256|ARBA:ARBA00004479}.
CC   -!- SIMILARITY: Belongs to the podocalyxin family.
CC       {ECO:0000256|ARBA:ARBA00007029}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KL225743; KFM02447.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A087QMJ3; -.
DR   STRING; 9233.A0A087QMJ3; -.
DR   Proteomes; UP000053286; Unassembled WGS sequence.
DR   GO; GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.
DR   GO; GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
DR   GO; GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
DR   GO; GO:0005902; C:microvillus; IEA:UniProtKB-SubCell.
DR   GO; GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
DR   GO; GO:0016477; P:cell migration; IEA:InterPro.
DR   GO; GO:0022407; P:regulation of cell-cell adhesion; IEA:InterPro.
DR   InterPro; IPR013836; CD34/Podocalyxin.
DR   InterPro; IPR017403; PODXL.
DR   PANTHER; PTHR12067; PODOCALYXIN; 1.
DR   PANTHER; PTHR12067:SF5; PODOCALYXIN; 1.
DR   Pfam; PF06365; CD34_antigen; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        394..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..269
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..92
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        109..269
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFM02447.1"
FT   NON_TER         489
FT                   /evidence="ECO:0000313|EMBL:KFM02447.1"
SQ   SEQUENCE   489 AA;  51817 MW;  A6172A07C9709F50 CRC64;
     LGVSSQDVTK TTPASPTEKG QITTTTDTSK MQGTTPTSKP GNPPSTSTSS AATVQGTTPT
     SKPGNPPTST VISPSTVQGT TPTSSPGNSS PTPTTSPHLP PATPEGLGTA VTSPPSVEAQ
     GGQPSDQLTS TATSTGVLTS SLSPGLKDYG ISSATAVTKQ PHFSPSSPGQ ELASSTRPGS
     IDTSVTPFDG SVSPTTRKAS LSLPPGSVNK VSEAATTPTL GTDQRSHDAS SVSTKPASAD
     QSPASAQPSA PVPGDQTASS SPGHQHPNAS FQNEVICKDQ VQNNWPTVYL KEAKTCAEWR
     TTSINISFFE SFCSTGQHAF NASRETCTVM LTSREPRSQH WAVQAVVHLP LDPEKVLEEL
     KEKKDKLEEL GIANITYDKM EREMVINDEF STPLIITIVT LAVSLLLIAA IYGCCHQRFS
     RKKDQQRLTE ELQTMENGYH DNPTLEVMET SSEMQEKKVN LNGELGDSWI VPLDTLMKED
     LEEEEDTHL
//