ID A0A087QRP8_APTFO Unreviewed; 1314 AA.
AC A0A087QRP8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Peroxidasin {ECO:0000313|EMBL:KFM03902.1};
DE Flags: Fragment;
GN ORFNames=AS27_10836 {ECO:0000313|EMBL:KFM03902.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM03902.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM03902.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM03902.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL225840; KFM03902.1; -; Genomic_DNA.
DR STRING; 9233.A0A087QRP8; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0140825; F:lactoperoxidase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR CDD; cd05746; Ig4_Peroxidasin; 1.
DR CDD; cd09826; peroxidasin_like; 1.
DR Gene3D; 1.10.640.10; Haem peroxidase domain superfamily, animal type; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR InterPro; IPR000483; Cys-rich_flank_reg_C.
DR InterPro; IPR019791; Haem_peroxidase_animal.
DR InterPro; IPR010255; Haem_peroxidase_sf.
DR InterPro; IPR037120; Haem_peroxidase_sf_animal.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR034828; Peroxidasin_Ig-like4.
DR InterPro; IPR034824; Peroxidasin_peroxidase.
DR PANTHER; PTHR11475; OXIDASE/PEROXIDASE; 1.
DR PANTHER; PTHR11475:SF54; PEROXIDASE; 1.
DR Pfam; PF03098; An_peroxidase; 1.
DR Pfam; PF07679; I-set; 4.
DR Pfam; PF13855; LRR_8; 2.
DR PRINTS; PR00457; ANPEROXIDASE.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SMART; SM00369; LRR_TYP; 5.
DR SMART; SM00082; LRRCT; 1.
DR SUPFAM; SSF48113; Heme-dependent peroxidases; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS50835; IG_LIKE; 4.
DR PROSITE; PS51450; LRR; 3.
DR PROSITE; PS50292; PEROXIDASE_3; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|PIRSR:PIRSR619791-2};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR619791-2};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR619791-2};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 211..299
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 307..393
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 398..483
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 486..577
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT BINDING 1039
FT /ligand="heme b"
FT /ligand_id="ChEBI:CHEBI:60344"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR619791-2"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFM03902.1"
FT NON_TER 1314
FT /evidence="ECO:0000313|EMBL:KFM03902.1"
SQ SEQUENCE 1314 AA; 147704 MW; 4D6B76A876193123 CRC64;
CPSRCLCFRT TVRCMHLMLE TIPDIPPQTN ILDLRFNHIK EIQPGDFRRL KNLNTLLLNN
NQIKQIVRRS FEDLENLKYL YLYKNEIQSI QQHAFNGLRS LEQLYLHFNN LESLEPETFS
DLPKLERLFL HNNKISRIHP GTFSQLESLK RLRLDSNALL CDCDLMWLAE LLKKYAEQGS
IQTAATCEAP RELHGRSIVT LTAQEFNCER PRITSEPHDV DVLLGNTVYF TCRAEGNPKP
AIIWLHNNNE IDMKDDNRLN LLQDGTLMIQ NTKESDKGVY QCMAKNIAGE VKTQEVVLRY
FGTPSKPTFV IQPQNTEVLI GESVTLECGV SGHPHPRISW TLGTGSPLPQ DSRFAITSSG
GLFIQNVTFS DQGQYNCNAS NTEGSIQATA RIIVQDSPRF LLIPTDQTVT EGQSVDFPCS
AEGHPPPVIA WTRAGGPLPS DRRHSILSTG TLRVMRVALH DQGQYECHAI SAIGVRTLPV
QLSVTPRVIP VFLHPPQDVV AETGQDVAIT CAAQGDPRPT ITWVKEGIQI TESGKFHISQ
DGTLAIQDLG VADQGRYECI ARNPFGFTSS AMQLTITATD VGRSGDTFVA TSIREAISSV
DHAINSTRTE LFSKRPKTPN DLLALFRYPR DPYTLETARA GEIFERTLQL IQEHVQQGLI
VDMNVTGYRY NDLVSPHYLN MIANLSGCSA HRRTPNCSDI CFHKKYRTHD GSCNNLQHPM
WGASLTAFQR LLKPAYQNGF NLPRGFSLAE DARDLPLPLP RLVSTAMVGT ETITPDDQFT
HMLMQWGQFL DHDMDQTVAA ISMSRFSDGA PCSKVCSNDP PCFSVMVPAN DPRVRNGRCM
FFVRSSPVCG SGMTSLLMNS VYAREQINHL TSYIDASNVY GSTEQESREL RDLSSQNGLL
KQGQAVPSSG KHLLPFAVGP PTECMRDENE SPVPCFLAGD HRANEQLGLT AMHTLWFREH
NRIAMELSAL NPHWDGDLLY HEARKIVGAQ MQHITYAQWL PKVLGEAGMK MLGEYKGYNP
NINAGILNAF ATAAFRFGHT LINPILYRLN ETFQPIRQGH IPLHKAFFSP FRITQEGGID
PLLRGLFGVP GKMRVPSELL NMELTEKLFS MAHSVSLDLA AINIQRGRDH GIPPYNDFRV
FCNLSSAQEF EDLRNEIKNL EIREKLRSLY GTTKNIDLFP ALMVEDLVPG TRVGPTLMCL
LTTQFRRLRD GDRFWYENPG VFTPAQLTQI RQTSLARVIC DNSDHIQQLQ RDVFRVASYP
QGMVGCEEIP AVDLRLWQDC CEDCQTRGQF RALSQRFRSK RSPGFSYPEE NPAK
//
