ID A0A087QVH1_APTFO Unreviewed; 1484 AA.
AC A0A087QVH1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 13-SEP-2023, entry version 31.
DE SubName: Full=Pappalysin-2 {ECO:0000313|EMBL:KFM05225.1};
DE Flags: Fragment;
GN ORFNames=AS27_08139 {ECO:0000313|EMBL:KFM05225.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM05225.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM05225.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM05225.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M43B family.
CC {ECO:0000256|ARBA:ARBA00008721}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR EMBL; KL225950; KFM05225.1; -; Genomic_DNA.
DR STRING; 9233.A0A087QVH1; -.
DR MEROPS; M43.005; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:InterPro.
DR CDD; cd00033; CCP; 2.
DR CDD; cd04275; ZnMc_pappalysin_like; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 3.30.300.320; -; 1.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006558; LamG-like.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR011936; Myxo_disulph_rpt.
DR InterPro; IPR000800; Notch_dom.
DR InterPro; IPR043543; PAPPA/PAPPA2.
DR InterPro; IPR008754; Peptidase_M43.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR NCBIfam; TIGR02232; myxo_disulf_rpt; 1.
DR PANTHER; PTHR46130; LAMGL DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46130:SF1; PAPPALYSIN-2; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF00066; Notch; 1.
DR Pfam; PF05572; Peptidase_M43; 1.
DR Pfam; PF00084; Sushi; 1.
DR SMART; SM00032; CCP; 4.
DR SMART; SM00560; LamGL; 1.
DR SMART; SM00004; NL; 2.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 3.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 2.
DR PROSITE; PS50923; SUSHI; 2.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT DOMAIN 1217..1286
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 1287..1342
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFM05225.1"
FT NON_TER 1484
FT /evidence="ECO:0000313|EMBL:KFM05225.1"
SQ SEQUENCE 1484 AA; 163150 MW; F13ACCF5C618203E CRC64;
PVPAAGVFDN CSHTASDKGW ALGIRALQLG GKKDARFFFS LRTDRAATAT EVTAYHRYRP
EAWTHLAASY DGQWMALYVD GARVGRAGGQ GGALHSTFMA SCRTLLLGGD AWGTAHAFRG
HLAGLALWQG ALSQPHLQRP FLEGVAGGVA GLALAAGFAI PEEHWAPFRE GAFPRQRVLP
SPPSPILWPL GPPACGQTAC DNVELVSHYN QHWPLRSGKA VRYRVVNLVE DGGGRPTVSR
EQVWRQHRAL SEAFRPYNIS WQLSLLEVRN SSLRRRAVLL GCEPSKVGNE RCDPECEHPL
TGYDGGDCRR PGRCFSWKRR DGVCHMECNN MLDDFDDGDC CDPRATDVAR TCFDPDSPQR
AYMSVKELKE ALQLNSTHFL NVYFASSVRE ELAGAATWPW DKEALSHLGG VVLNPAYYGM
HGHTNTMIHE VGHVLGLYHV FKGVSERESC DDPCRETTPS METGDLCADT APTPKSKLCR
DPDPTNDTCG QTHFTGTPFN NYMSYTDDDC TNTFTPNQVA RMHCYLDLVY QRWGQSKKPA
PIPIPPMVTG QTQDSLSIYW LPPISGVIHE REQDTICDDC AEDGTFRQYV HEASSPRVCD
SSGYWTPEEA EGPPDVDQPC EPSLQAWSPE LHLYHMNMTV PCPQPDGCIL ELRFLHPVYP
DSLTLWTTYL STGSPKVLSD IEVLTEQGES IHLGPLDTFC DVPFTVKLNI PKKVSGVKIY
TFDERMEIDT ALLTSMPHSS LCATCKLIQY RVLRDPPFAN GSPAAPAQAH LQSIDTEVTP
GQVYHYQVQA VSGTTSGEAS PLLVHVHGAP YCGDGKVTTS LEEECDDGDL LDGDGCSRKC
KKEKGFNCVG EPSLCYVHDG DGVCELFEKT SSVLDCGPYT PNGYVDLWAV KAYASHHDAK
YCPASLVTGE PVVKVCKSHL HNVPKDLSLS AWFPCTPSRD NAQDADEERM TLGDEGVWLK
VCFERPVVPT SLLVFLASDG TVPSNQRKPR VTVQLSDVDG LNHSLGMYEL SCQHNPLVIN
VTHGQEDPSH WAASVLLNFS SPLVGIAAVA LRTSAQLGSD PTTCLLQHEE GRGHQRYSCV
HGACAVSGSC MRPLLAHTAT LNCTSNSPRH MVCTIACEKG FVLRSSNGKS LGSMQQEVVL
TCSSGRWDRS VTCDPVDCGV PDQSHVYYAE FSCPKGTTYL QRCSFSCIDP AKLQGTNQWL
TCLEDGLWSL PEAYCKLECD MPPVVANAKL LVLRCLQGNH DVGSVCRYKC KPGYHVAENA
AGKLKKKFLK VQCLESGQWE EGHCVPVVCE PPPPVFEGMY NCTQGFELDS QCILNCEPQG
QQVPIVCTKE GLWTEEFKLC ENLQGTCPPP PELNFVEYKC EQGHGIGAVC IPSCIIPPSD
PVILPENVTA ETMDHHLQPT RVQHIVCTGR LRWYPDPSVI HCIQSCEPFQ ADGWCDTINN
RAYCQYDGGD CCSSTLSSRK VIPFAADCDQ DECTCRDPAA EENQ
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