ID A0A087QY06_APTFO Unreviewed; 633 AA.
AC A0A087QY06;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Double-strand-break repair protein rad21 {ECO:0000313|EMBL:KFM06110.1};
GN ORFNames=AS27_11147 {ECO:0000313|EMBL:KFM06110.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM06110.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM06110.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM06110.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May promote apoptosis. {ECO:0000256|ARBA:ARBA00043845}.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere
CC {ECO:0000256|ARBA:ARBA00004584}. Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the rad21 family.
CC {ECO:0000256|ARBA:ARBA00009870}.
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DR EMBL; KL225998; KFM06110.1; -; Genomic_DNA.
DR RefSeq; XP_009275478.1; XM_009277203.2.
DR RefSeq; XP_009275479.1; XM_009277204.2.
DR RefSeq; XP_019327067.1; XM_019471522.1.
DR AlphaFoldDB; A0A087QY06; -.
DR STRING; 9233.A0A087QY06; -.
DR GeneID; 103897221; -.
DR KEGG; afor:103897221; -.
DR CTD; 5885; -.
DR OrthoDB; 5481351at2759; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0008278; C:cohesin complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR CDD; cd21792; Rad21_Rec8_M_NXP1-like; 1.
DR Gene3D; 1.10.10.580; Structural maintenance of chromosome 1. Chain E; 1.
DR InterPro; IPR049589; NXP1_M-like.
DR InterPro; IPR039781; Rad21/Rec8-like.
DR InterPro; IPR006909; Rad21/Rec8_C_eu.
DR InterPro; IPR006910; Rad21_Rec8_N.
DR InterPro; IPR023093; ScpA-like_C.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR12585:SF20; DOUBLE-STRAND-BREAK REPAIR PROTEIN RAD21 HOMOLOG; 1.
DR PANTHER; PTHR12585; SCC1 / RAD21 FAMILY MEMBER; 1.
DR Pfam; PF04824; Rad21_Rec8; 1.
DR Pfam; PF04825; Rad21_Rec8_N; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Centromere {ECO:0000256|ARBA:ARBA00023328};
KW Chromosome partition {ECO:0000256|ARBA:ARBA00022829};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286}.
FT DOMAIN 1..103
FT /note="Rad21/Rec8-like protein N-terminal"
FT /evidence="ECO:0000259|Pfam:PF04825"
FT DOMAIN 577..630
FT /note="Rad21/Rec8-like protein C-terminal eukaryotic"
FT /evidence="ECO:0000259|Pfam:PF04824"
FT REGION 236..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 423..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 426..440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 488..509
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 535..549
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 633 AA; 72081 MW; E1EE2BBC53D83C3E CRC64;
MFYAHFVLSK RGPLAKIWLA AHWDKKLTKA HVFECNLESS VESIISPKVK MALRTSGHLL
LGVVRIYHRK AKYLLADCNE AFIKIKMAFR PGVVDLPEEN REAAYNAITL PEEFHDFDQP
LPDLDDIDVA QQFSLNQSRV EEITMREEVG NISILQDNDF GDFGMDDREM MREGSAFEDD
MLVSTSASNL LLEPEQSTSH LNEKSNHLEY EDQYKDDNFG EGNDGGILDD KLLSNNDGGI
FDDPPALSES GVMMPEQPPH DDMDDDDNVS MGGPDSPDSV DPVEPLPTMT DQTTLVPNEE
EAFALEPIDI TVKETKAKRK RKLIVDSVKE LDSKTIRAQL SDYSDIVTTL DLAPPTKKLM
MWKETGGVEK LFSLPAQPLW NNRLLKLFTR CLTPLVPEDL RKRRKGGEAD NLDEFLKDFE
NPEVPREEQQ QQQQQQQRDV IDEPILEEPS RLQESMMEGS RTNLDESVMP PPPPQTGVKR
KLQQVEPEPV LPHPPAQQLE IPPVEMPPEE PQNICQLIPE LELLPEKEKE KEKEKEEEEE
EEEEDGTGGD QDQEERRWNK RTQQMLHGLQ RALAKTGAES ISLLELCRNT NRKQAAAKFY
SFLVLKKQQA IELTQEEPYS DIIATPGPRF HII
//
