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Database: UniProt
Entry: A0A087QYU7_APTFO
LinkDB: A0A087QYU7_APTFO
Original site: A0A087QYU7_APTFO 
ID   A0A087QYU7_APTFO        Unreviewed;       879 AA.
AC   A0A087QYU7;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   20-DEC-2017, entry version 14.
DE   SubName: Full=Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 {ECO:0000313|EMBL:KFM06401.1};
GN   ORFNames=AS27_02522 {ECO:0000313|EMBL:KFM06401.1};
OS   Aptenodytes forsteri (Emperor penguin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC   Aptenodytes.
OX   NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM06401.1, ECO:0000313|Proteomes:UP000053286};
RN   [1] {ECO:0000313|EMBL:KFM06401.1, ECO:0000313|Proteomes:UP000053286}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM06401.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KL226002; KFM06401.1; -; Genomic_DNA.
DR   RefSeq; XP_009275926.1; XM_009277651.2.
DR   RefSeq; XP_009275927.1; XM_009277652.1.
DR   RefSeq; XP_009275928.1; XM_009277653.2.
DR   RefSeq; XP_009275929.1; XM_009277654.1.
DR   GeneID; 103897594; -.
DR   CTD; 8509; -.
DR   Proteomes; UP000053286; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015016; F:[heparan sulfate]-glucosamine N-sulfotransferase activity; IEA:InterPro.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR021930; Heparan_SO4_deacetylase.
DR   InterPro; IPR037359; NST/OST.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000863; Sulfotransferase_dom.
DR   PANTHER; PTHR10605; PTHR10605; 1.
DR   Pfam; PF12062; HSNSD; 1.
DR   Pfam; PF00685; Sulfotransfer_1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053286};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW   Transferase {ECO:0000313|EMBL:KFM06401.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     20     38       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       26    510       HSNSD. {ECO:0000259|Pfam:PF12062}.
FT   DOMAIN      600    850       Sulfotransfer_1. {ECO:0000259|Pfam:
FT                                PF00685}.
SQ   SEQUENCE   879 AA;  101472 MW;  D13BE8F7A2F7AB0C CRC64;
     MIQLWKVVRH VRQLELHRLI LLLIAFSLIS MCILAYYVTN SPKIKEPPPL PFSDCSNQHR
     ILIPPQASWR LTKSVDTSRT DPVVLVFVES IYSQLGQEIV AILESSRFKY RTEIAPGKGD
     MPTLTDKDRG RYALIIYENI LKYVNLDAWN RELLDKYCVE YGVGIIGFFK ANENSLLSAQ
     LKGFPLFLHS NLGLRDYHIN PSAPLLYVTR ANEVEQGPLP GDDWTVFQSN HSTYEPVLLA
     STKSSESIPH LATHKALHAT VVQDLGLHDG IQRVLFGNNL NFWLHKLIFV DAIAYLTGKR
     LCLTLDRYIL VDIDDIFVGK EGTRMKVSDV EALLSTQNKL RTLVPNFTFN LGFSGKFYHT
     GTDEEDEGDD MLLKHRKEFW WFPHMWSHMQ PHLFHNVTVL AEQMKLNKQF AVEHGIPTDL
     GYAVAPHHSG VYPVHTQLYE AWKSVWSIQV TSTEEYPHLR PARYRRGFIH NGIMVLPRQT
     CGLFTHTIFY NEYPGGSKEL DKSIRGGELF LTVLLNPISI FMTHLSNYGN DRLGLYTFES
     LVKFVQCWTN LRLQTLPPVQ LAKKYFEIFP QEKNPLWQNP CDDKRHKDIW SKEKTCDRLP
     KFLIVGPQKT GTTAVHFFLT MHPAVTSNFP SPSTFEEIQF FNGPNYHKGI DWYMEFFPIP
     SNASTDFMFE KSANYFDTEV VPKRGAALLP RAKIITVLIN PADRAYSWYQ HQRAHNDPVA
     LNYTFYQVIS AKSQAPQELR NLQSRCLLPG WYSTHLERWL TYYPSGQLLI VDGQELRHNP
     ASVMDNIQKF LGVTPLFNYT QALRFDEAKG FWCQLLDGGK TKCLGKSKGR KYPDMDSSSR
     LFLRDFYREH NIELSKLMNR LGQPLPTWLR EELQNSSWS
//
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