ID A0A087R3N2_APTFO Unreviewed; 983 AA.
AC A0A087R3N2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=GTPase-activating Rap/Ran-GAP domain-like 3 {ECO:0000313|EMBL:KFM08086.1};
DE Flags: Fragment;
GN ORFNames=AS27_03384 {ECO:0000313|EMBL:KFM08086.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM08086.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM08086.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM08086.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL226076; KFM08086.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087R3N2; -.
DR STRING; 9233.A0A087R3N2; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR001180; CNH_dom.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR PANTHER; PTHR15711:SF62; GTPASE-ACTIVATING RAP_RAN-GAP DOMAIN-LIKE PROTEIN 3; 1.
DR PANTHER; PTHR15711; RAP GTPASE-ACTIVATING PROTEIN; 1.
DR Pfam; PF00780; CNH; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SMART; SM00036; CNH; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50219; CNH; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286}.
FT DOMAIN 174..390
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
FT DOMAIN 474..784
FT /note="CNH"
FT /evidence="ECO:0000259|PROSITE:PS50219"
FT REGION 792..817
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 899..967
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 792..812
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 899..919
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 921..967
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFM08086.1"
FT NON_TER 983
FT /evidence="ECO:0000313|EMBL:KFM08086.1"
SQ SEQUENCE 983 AA; 111002 MW; A7351906257B7D56 CRC64;
LMKCFYSSSV SEDLGCRRGE FSRKHYGSVE LLISSDADGA IQRAGRFRVE NGSSGENTDY
TPGTWHRTDV HLENPECHTR WYFKYFLGKV HQNYIGTDAE KNPFFLSVVL SDQNNQRVPQ
YHSILWRKTG TQKICLPYSP TKTLSVKSIL SAMSLDKFEK SPREIFHPEI QKDLLVLEEQ
EGSVNFKFGV LYAKDGQLTD DEMFSNETGS ESFQRFLHLL GDTITLKGWT GYRGGLDTKN
DTTGTCSIYT VFQGHEIMFH VSTMLPYSRE NKQQVERKRH IGNDIVTIVF QEGEESSPAF
KPSMIRSHFT HIFALVRYNK QNDSYRLKIF SEESVPLFGP PLPSPPVFTN HQEFRDFVLV
KLINGEKATL ETPTFSQKRQ RTLDMLIRSL YQDLVPDLHK VNNMLNRRSF SDVLPESPKS
TRKKEEARQA EFVRLGQALK LKTTVKGDAT ANLATTSFCK KEPWESQSFC SNFPHEVVCA
DSWGQSLLVS TDAGILLVDD GQPSVQVFDK TLQIKQMHVL EALDLLIART DKGKDSRLLV
FRLSAVQKDI ETKQMIRSKY DCRENKLERT KGCHLYAINT HHGSELRIVV AIRNKLLLVT
KKYNPRNSLT SSSLLSSSES PVEEFQYIRE ICLSDPPVIM TLVDGPTGDS DNMICVAYRH
QFDLVNESTG ESYRLHHVET NKVNFVAAID VYEDGEAGLL LCYNYVCQYR KVYPFNGSSP
LIQPSAYDFH FSWNQVPYAV VCAFPYILAF TTDSIEIRLV VNGNLVHTAV VPELQLVASR
SDIYFKATTA VSGSSDSSSK EMSSSSPQTP TAYEMPERPL SSLEGEVLCK NLYKIPLSNL
VGRSIERPLK SPLAPKVITT TTSSGIASLP VTHSLSLSRM EIKEIASRTR KELLGLLDEP
IPKTESAQKQ KKVPRRQSDP KQGAVRSTSS DRIISSSFES YSEGCHLSTS SDPDTLANRE
ESSPSSYPFQ LISLYDEDII DLK
//
