ID A0A087R6F4_APTFO Unreviewed; 879 AA.
AC A0A087R6F4;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE SubName: Full=Laminin subunit alpha-2 {ECO:0000313|EMBL:KFM09058.1};
DE Flags: Fragment;
GN ORFNames=AS27_14868 {ECO:0000313|EMBL:KFM09058.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM09058.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM09058.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM09058.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular
CC matrix, basement membrane {ECO:0000256|ARBA:ARBA00004302}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00460}.
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DR EMBL; KL226140; KFM09058.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087R6F4; -.
DR STRING; 9233.A0A087R6F4; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0005604; C:basement membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00055; EGF_Lam; 6.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 2.10.25.10; Laminin; 6.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR000034; Laminin_IV.
DR InterPro; IPR008211; Laminin_N.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR10574:SF291; LAMININ SUBUNIT ALPHA-2; 1.
DR PANTHER; PTHR10574; NETRIN/LAMININ-RELATED; 1.
DR Pfam; PF00052; Laminin_B; 1.
DR Pfam; PF00053; Laminin_EGF; 8.
DR Pfam; PF00055; Laminin_N; 1.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00180; EGF_Lam; 7.
DR SMART; SM00281; LamB; 1.
DR SMART; SM00136; LamNT; 1.
DR SUPFAM; SSF57196; EGF/Laminin; 7.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS01248; EGF_LAM_1; 3.
DR PROSITE; PS50027; EGF_LAM_2; 5.
DR PROSITE; PS51115; LAMININ_IVA; 1.
DR PROSITE; PS51117; LAMININ_NTER; 1.
PE 4: Predicted;
KW Basement membrane {ECO:0000256|ARBA:ARBA00022869};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00460}; Extracellular matrix {ECO:0000256|ARBA:ARBA00022869};
KW Laminin EGF-like domain {ECO:0000256|ARBA:ARBA00023292,
KW ECO:0000256|PROSITE-ProRule:PRU00460};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW Secreted {ECO:0000256|ARBA:ARBA00022869}.
FT DOMAIN 1..249
FT /note="Laminin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51117"
FT DOMAIN 377..431
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 432..480
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 501..686
FT /note="Laminin IV type A"
FT /evidence="ECO:0000259|PROSITE:PS51115"
FT DOMAIN 720..769
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 770..827
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 828..879
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DISULFID 377..389
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 407..416
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 451..460
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 739..748
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 798..807
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 852..861
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT DISULFID 864..878
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00460"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFM09058.1"
FT NON_TER 879
FT /evidence="ECO:0000313|EMBL:KFM09058.1"
SQ SEQUENCE 879 AA; 96957 MW; AB0A50F369194BD3 CRC64;
GLFPAVLNLA TNALITTNAT CGEKGREMYC KLVEHVPGQP ARNPQCRICD QRSRVPHQRH
PITNAIDGKN TWWQSPSIQN GIEYHYVTVT LDLQQIFQIA YVIVKAANSP RPGNWILERS
LDGVDYQPWQ YYAITDSECL TRYNIHPRPG TPSYVKDDEV ICTSYYSKIH PLENGEIHTS
LINGRPSADD PSRVLLEFTS ARFIRLRFQR IRTLNADLMM FAHKDPNEID PIVTRRYYYS
IKDISVGGMC ICSGHAKACP LDPATNKSVC QCEHNTCGET CDRCCPGFNQ KPWHAGTFLV
KHECEPCNCH GKTEACYYDQ DVADRNQSLN VRGEYIGGGV CVNCTSHTGG INCETCVDGY
FRPKGVLPDN PDPCQPCSCD PNGSLHDTCV KDEKHAEGDM LPGFCHCKTG YAGESCNRCA
LGYTGYPECL PCNCSLKGSA NVDPCIGPCI CKEHVEGENC DRCKPGFFNL QRNNPKGCEE
CFCSGKTNVC THSHLTYRSM EDMNGWYLTG LLGLTRVTPR QKRFDGHQQF SISNVAARKV
LPQTYYWSAP SSYLGNKVAA AGGHLTFTVS YDFTKEEETV QLMVQSDVII EGGDLRISTP
KGGIHLQPSE EHTEEIVLKP ESFSVHGTDV PVSRREFMTI LANVKRILIR ATYSYGMNAI
YRLRSVSIEA ADHTSTGRKV ASAVELCDCP PGYDGTSCES CWPRHRRVNG TIFGGVCAPC
TCFGHAELCD DITGECLDCK HNTGGSYCDR CLPGFYGEPT KGTAEDCQLC ACPLNIPSNN
FSPTCHFDRS HGLICDECPA GYVGPRCERC AEGYFGQPLI PGGSCQPCQC NDNLDFSIPG
SCDSLSGACL ICKPGTTGQY CERCADGYFG DALDARNCQ
//
