ID   A0A087R7H6_APTFO        Unreviewed;       547 AA.
AC   A0A087R7H6;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=NADPH oxidase 1 {ECO:0000313|EMBL:KFM09430.1};
DE   Flags: Fragment;
GN   ORFNames=AS27_00750 {ECO:0000313|EMBL:KFM09430.1};
OS   Aptenodytes forsteri (Emperor penguin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC   Aptenodytes.
OX   NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM09430.1, ECO:0000313|Proteomes:UP000053286};
RN   [1] {ECO:0000313|EMBL:KFM09430.1, ECO:0000313|Proteomes:UP000053286}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM09430.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; KL226172; KFM09430.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A087R7H6; -.
DR   STRING; 9233.A0A087R7H6; -.
DR   Proteomes; UP000053286; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR   Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 1.
DR   InterPro; IPR000778; Cyt_b245_heavy_chain.
DR   InterPro; IPR013112; FAD-bd_8.
DR   InterPro; IPR017927; FAD-bd_FR_type.
DR   InterPro; IPR013130; Fe3_Rdtase_TM_dom.
DR   InterPro; IPR013121; Fe_red_NAD-bd_6.
DR   InterPro; IPR039261; FNR_nucleotide-bd.
DR   InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR   PANTHER; PTHR11972; NADPH OXIDASE; 1.
DR   PANTHER; PTHR11972:SF71; NADPH OXIDASE 1; 1.
DR   Pfam; PF08022; FAD_binding_8; 1.
DR   Pfam; PF01794; Ferric_reduct; 1.
DR   Pfam; PF08030; NAD_binding_6; 1.
DR   PRINTS; PR00466; GP91PHOX.
DR   SFLD; SFLDS00052; Ferric_Reductase_Domain; 1.
DR   SFLD; SFLDG01168; Ferric_reductase_subgroup_(FRE; 1.
DR   SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR   SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR   PROSITE; PS51384; FAD_FR; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        86..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        148..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        184..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          264..374
FT                   /note="FAD-binding FR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51384"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFM09430.1"
FT   NON_TER         547
FT                   /evidence="ECO:0000313|EMBL:KFM09430.1"
SQ   SEQUENCE   547 AA;  62824 MW;  897156F0DD181B6A CRC64;
     WLGINIFLFT YYFLFFNWDE RYFYTRTILR SALAWARASA KCLNFNSMLI LLPVCRNLLS
     FLRGTCSCCR RTLRKQLDHN LTFHKLVAYA LALLTAVHTI AHLFNLERYN HSQQATDGSL
     PAVLSKMHLQ GSNKWLNPIH SNQTTVEYVA FTTIPGLTGV IITLALILMV TSSTEFIRRN
     YFEVFWYTHH LFLIYFAGLV IHGIAGLVRG QTEESIEEVH PHRCAEYLTH KDKNCSHNCC
     KDPEFGSIPA ESWKWVLAPV LLYVFERILR VWRARQKVVV TKVVMHPARV LELQMQKKGF
     CMEVGQYIFV NCPAISLLEW HPFTLTSAPE EDFFSIHIRA AGDWTERLID TFQQQKLEKP
     RIEVDGPFGT ASEDVFQYEV AMLVGAGIGV TPFASILKSI WYKFQQADQT LKTKKIYFYW
     LCRDTGAFAW FNDLLASLEQ KMAESGKADF LTYRLFLTGW DTSIANNVAL HFDTPTDTVT
     GLRHKTIFGR PMWNSEFAAV AAAHPRSVVG VFLCGPGALA KSLQKSCHQH SSLDPRKVKF
     YFNKENF
//