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Database: UniProt
Entry: A0A087RA60_APTFO
LinkDB: A0A087RA60_APTFO
Original site: A0A087RA60_APTFO 
ID   A0A087RA60_APTFO        Unreviewed;       395 AA.
AC   A0A087RA60;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   08-MAY-2019, entry version 23.
DE   SubName: Full=Inward rectifier potassium channel 16 {ECO:0000313|EMBL:KFM10364.1};
GN   ORFNames=AS27_15190 {ECO:0000313|EMBL:KFM10364.1};
OS   Aptenodytes forsteri (Emperor penguin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC   Aptenodytes.
OX   NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM10364.1, ECO:0000313|Proteomes:UP000053286};
RN   [1] {ECO:0000313|EMBL:KFM10364.1, ECO:0000313|Proteomes:UP000053286}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM10364.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   EMBL; KL226236; KFM10364.1; -; Genomic_DNA.
DR   Proteomes; UP000053286; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR008061; K_chnl_inward-rec_Kir5.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   PANTHER; PTHR11767:SF24; PTHR11767:SF24; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01678; KIR5CHANNEL.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053286};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|EMBL:KFM10364.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     46     68       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    117    142       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       10    146       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      154    321       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   SITE        133    133       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   395 AA;  45554 MW;  977C28691E7CDFD4 CRC64;
     MKRLQKRFLH KDGSCNVYFK HIFGEWESYV VDIFTTLVDI KWRHMFVIFS LSYVLSWLFF
     GLVFWLIAIQ HGDLFNDEEI TPCVANVHSF TGAFLFSLET QTTIGYGYRC VTEECSVAIL
     MVILQSVLSC IIDTFIIGAA LAKMATARKR AQTIRFSYYA VVGLRDDKFC LMWRIGDFRP
     NHMVEGSVRA QLLRYKEDKE GRMTMEYKDL KLLNDQIILV TPVTVVHEID SESPLYGLDR
     KALAKDNFEI LVTFVYTGDS TGTSHQSRSS YVPREILWGH RFNDVLHVKK KYYKVDCLQF
     EETTEVYAPH CSAMQLDRKE QEWNRTEKTR EKEAETSALE IKSFSTNQKS FSAVALITSC
     EDPEDTVTAV NQHSGEVSYQ KASVTLSRLP IESQI
//
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