ID A0A087RC83_APTFO Unreviewed; 2506 AA.
AC A0A087RC83;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Filamin-B {ECO:0000313|EMBL:KFM11087.1};
DE Flags: Fragment;
GN ORFNames=AS27_11726 {ECO:0000313|EMBL:KFM11087.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM11087.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM11087.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM11087.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the filamin family.
CC {ECO:0000256|ARBA:ARBA00009238}.
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DR EMBL; KL226288; KFM11087.1; -; Genomic_DNA.
DR STRING; 9233.A0A087RC83; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 24.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR044801; Filamin.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR001298; Filamin/ABP280_rpt.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR38537; JITTERBUG, ISOFORM N; 1.
DR PANTHER; PTHR38537:SF17; JITTERBUG, ISOFORM N; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF00630; Filamin; 24.
DR SMART; SM00033; CH; 1.
DR SMART; SM00557; IG_FLMN; 24.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF81296; E set domains; 24.
DR PROSITE; PS50021; CH; 1.
DR PROSITE; PS50194; FILAMIN_REPEAT; 24.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 42..145
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT REPEAT 152..250
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 252..349
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 350..446
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 447..539
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 543..639
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 640..742
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 743..841
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 842..937
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 938..1030
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1031..1125
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1126..1225
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1226..1318
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1319..1414
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1415..1511
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1512..1607
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1662..1720
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1720..1812
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1810..1898
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1901..1993
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 1991..2089
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2092..2184
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2186..2279
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2283..2375
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT REPEAT 2411..2505
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFM11087.1"
FT NON_TER 2506
FT /evidence="ECO:0000313|EMBL:KFM11087.1"
SQ SEQUENCE 2506 AA; 266959 MW; 96BB0127CBAD86CE CRC64;
DSKAIVDGNL KLILGLIWTL ILHYSISMPV WEDEGDDDAK KQTPKQRLLG WIQNKIPYLP
ITNFNQNWQD GKALGALVDS CAPGLCPDWE TWDPKKPVDN AREAMQQADD WLGVPQVITP
EEIIHPDVDE HSVMTYLSQF PKAKLKPGAP LKPKLNPKKA RAYGRGIEPH GNMVKQPAIF
TVDTISAGQG DLMVFIEDPE GNREEAKITP SSDKNKTYSV QYVPKVTGPH KVSVLFAGQH
ISKSPFEVNV DKAQGDASKV TAKGPGLEAT GNIANKPTYF DLYTAGAGVG DVNVEVEDPQ
GRSLAEVAVE DKGNQVYRCT YKPVQAGPHI VKVTFAGEAI PKTPCTVLVG EACNPNACRA
TGRGLQPKGV RMRETADFKV DTRAAGSGDL GVTIKGPKGL EELVKQKGFM DGVYAFEYYP
ATPGKYVVTI TWGGHNIPKS PFEVQVGHEA GPQKVRAWGP GLHEGIVGKS ADFVVESIGT
EVGSLGFAIE GPSQAKIECD DKNDGSCDVK YWPKEPGEYA VHIMCDDEDI KDSPYMAFIR
PASGDFNPDK VKAYGPGLER TGCIVNNPAE FTVETKDAGK APLKMYAQDG EGNPIDIQIK
SKPDGVFACS YVPVKPIKHT ISVVWGGANV PNSPFRVLIG QGSHPQKVKV FGPGVERTGL
KANEPTHFTV DCTDAGEGDV SVGIKCDARV VSDEEEDIDF DIIHNANDTF TVKYAPPAAG
RYTIKVLFAG EEIPASPFRI KVDPSHDASK VKAEGPGLNK TGVENGKPTH FTVFTKGAGK
APLDVQFSSP VPGEAVADLD IIDNYDYSHT VRYTPIQQGP MKVLVTYGGD PIPKSPFTVG
VAAPLDLSKV KVNGLENRVE VGKDQEFVID TKGAGGQGKL DVNISSPMRK AVPCLVEPVL
GKECSTAKYI PREEGLYVVD VSYDGNPIPG SPYTVEATLP PDPSKVKAHG PGLRGGLVGK
PAQFTIDTKG AGTGGLGLTV EGPCEAKIEC SDNGDGTCSV SYLPTKPGEY FVNILFEEVH
IPGSPFKADI EMPFDASKVI ATGPGLERGK VGEAGLLNVD CTEAGPGDLR VDMVSDAGSK
AEVQIDDNKD GTYVVTYVPL SAGMYTIKMR YGGEQVPKFP ARVKVEPAVD TSRVKVFGPG
VEGKDVFREA TTEFTVDARP LTKAGGDHIR TQITSPSGSP ADCLIQDNAD GTYSVEYTPF
EKGPHTVNVT YDGVPVPNSP FRVNVTEGCH PSRVKAQGPG LKEAFTNQPN AFSVVTRGAG
IGGLGITVEG PSESKISCKD NKDGSCSAEY VPYVPGDYDV NITYGGEHIP GSPFKVPVKD
VVDPSKVKIA GPGLGTAVRA KIPQSFTVDT SKAGVAPLEV VVAGPRGVVE PVNVVDNGDG
THTVVYTPTQ EGPYMVSVKY ADEEIPRSPF KVKVLPTYDA SKVTASGPGL SSYGIPASLP
VEFAVDAKDA GQGLLAVRIT DQEGKPKRAD IHDNKDGTYT VTYVPDKTGR YTIGVKYGGD
DIPSSPYRIR ASPAGDASKC LATGPGIAPT VKTGEEVGFV VDAKSAGKGK VTCTVLTPDG
TEAEADVVEN EDGTYDIFYT AAKPGTYVIY VRFGGVDIPN SPFTVMAVDA DDAVVRSQEP
VGTSPPGFRP WVTEEAYVPV GDMNGMGFRP FDMVIPFAVR KGEITGEVHM PSGKTDTPDI
VDNKDGTVTV RYAPTEVGLH EMHIKYMGKH IPESPLQFYV NYPNSGSVSA YGPGLIYGVA
NKPATFTIVT EDAGEGGLDL AIEGPSKAEI SCIDNKDGTC TVTYLPTLPG NYSILVKYND
KHIPGSPFTA KITDDNRRRS QVKLGSAADF LLDINETDLS LLTASIKAPS GRDEPCLLKR
LPNNHIGISF IPREVGEHLV SIKKNGSHVP NSPVTIMVVQ SEIGDARRAR VFGRGLVEGR
TFEMCDFIVD TRDAGYGGIS LAVEGPSKVD IQTEDLEDGT CKVSYFPTVP GVYIVSTKFA
DEHIPGSPFT VKISGEGRVK ESITRTRRAP SVATVGSICD LNLKIPEIDC GDMTAQVTSP
SGRNFDAEIV EADKNTYCVR FVPQEMGVHT VDVKYRGQPV PGSPFQFTVG PLGEGGAHKV
RAGGPGLERG ETGVPAEFSI WTREAGAGGL SIAVEGPSKA EIAFEDHKDG SCGVSYIVQE
PGNYEVSIKF NDEHIPESPY LVPVIAPSDD ARRLTVTSLQ ESGLKVNQPA SFAIRLNGAK
GKIDAKVHSP SGAVEECHVS ELEPDKYAVR FIPHENGIHS IDVKFNGSHV VGSPFKVRVG
EPGQAGNPAL VTAYGSGLES GTTGLQSEFF INTTKAGPGT LSVTIEGPSK VKMDCQETPE
GYKVMYTPMA PGNYLIGVKY GGPNHIVGSP FKAKVTGQRL VSPGSANETS SILVESVTRS
STETCYSAIP KSTSDASKVV SRGAGLSKAF VGQKSSFSVD CSKAGSNMLL VGVHGPTIPC
EEVSIKHLGS HQYNVMYVVK ERGDYILAVK WGDEHIPGSP FHVTVP
//
