ID A0A087REZ9_APTFO Unreviewed; 474 AA.
AC A0A087REZ9;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 22-FEB-2023, entry version 31.
DE SubName: Full=Ras-GEF domain-containing family member 1C {ECO:0000313|EMBL:KFM12053.1};
DE Flags: Fragment;
GN ORFNames=AS27_12040 {ECO:0000313|EMBL:KFM12053.1};
OS Aptenodytes forsteri (Emperor penguin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC Aptenodytes.
OX NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM12053.1, ECO:0000313|Proteomes:UP000053286};
RN [1] {ECO:0000313|EMBL:KFM12053.1, ECO:0000313|Proteomes:UP000053286}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM12053.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL226335; KFM12053.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A087REZ9; -.
DR STRING; 9233.A0A087REZ9; -.
DR Proteomes; UP000053286; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00155; RasGEF; 1.
DR CDD; cd06224; REM; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR019804; Ras_G-nucl-exch_fac_CS.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF186; RAS-GEF DOMAIN-CONTAINING FAMILY MEMBER 1C; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS00720; RASGEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000053286}.
FT DOMAIN 36..166
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 206..454
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFM12053.1"
FT NON_TER 474
FT /evidence="ECO:0000313|EMBL:KFM12053.1"
SQ SEQUENCE 474 AA; 54532 MW; E52DE43777811875 CRC64;
EGMPQTLSST SMFTPCGFSP HLHTSKEDEQ GGLIFQDGNL TSASLDALIQ HLIPTTDYYP
EKAYIFTFLL SSRLFIEPHE LLSRVCHKCI EQQRLDDPVL DKARIRKFGP KILQLLTEWT
ETFPYDFQEE RMIGHLKDMI HRIAPCDEAY WKKMNQLLQT LNQKLATLSH GQEGIVKISA
TVSDKLVAFK SKPPSIQREI LSVCSDPYTL AQQLTHVELE RLSHIGPEEF VQAFVHKDPL
DGTKTCFSEQ KKTSNLEAYV KWFNRLCYLV ATEICMPAKK KQRAQVIEFF IDVARECFNI
GNFNSLMAII SGMNMSPVSR LKKTWSKVKT AKFFILEHQM DPTGNFYNYR TALRGAAHRS
LTAHSNREKI VIPFFSLLIK DIYFLNEGCA NRLPNGHVNF EKFLELAKQV GEFITWKQVE
CPFEQDPNII HYLHTAPIFT EDGLYLASYE SESPENQTEK DRWKSLRSTI LGKT
//
