ID   A0A087RF22_APTFO        Unreviewed;       180 AA.
AC   A0A087RF22;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 37.
DE   RecName: Full=Pituitary homeobox 1 {ECO:0000256|ARBA:ARBA00039560};
DE   AltName: Full=Homeobox protein PITX1 {ECO:0000256|ARBA:ARBA00041925};
DE   AltName: Full=Paired-like homeodomain transcription factor 1 {ECO:0000256|ARBA:ARBA00042847};
DE   Flags: Fragment;
GN   ORFNames=AS27_12067 {ECO:0000313|EMBL:KFM12076.1};
OS   Aptenodytes forsteri (Emperor penguin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae;
OC   Aptenodytes.
OX   NCBI_TaxID=9233 {ECO:0000313|EMBL:KFM12076.1, ECO:0000313|Proteomes:UP000053286};
RN   [1] {ECO:0000313|EMBL:KFM12076.1, ECO:0000313|Proteomes:UP000053286}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_AS27 {ECO:0000313|EMBL:KFM12076.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00108}.
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DR   EMBL; KL226335; KFM12076.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A087RF22; -.
DR   Proteomes; UP000053286; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR016233; Homeobox_Pitx/unc30.
DR   InterPro; IPR003654; OAR_dom.
DR   PANTHER; PTHR45882:SF1; PITUITARY HOMEOBOX 1; 1.
DR   PANTHER; PTHR45882; PITUITARY HOMEOBOX HOMOLOG PTX1; 1.
DR   Pfam; PF03826; OAR; 1.
DR   PIRSF; PIRSF000563; Homeobox_protein_Pitx/Unc30; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
DR   PROSITE; PS50803; OAR; 1.
PE   4: Predicted;
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000313|EMBL:KFM12076.1};
KW   Homeobox {ECO:0000256|PROSITE-ProRule:PRU00108,
KW   ECO:0000313|EMBL:KFM12076.1};
KW   Nucleus {ECO:0000256|PROSITE-ProRule:PRU00108};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053286}.
FT   DOMAIN          1..14
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DOMAIN          146..159
FT                   /note="OAR"
FT                   /evidence="ECO:0000259|PROSITE:PS50803"
FT   DNA_BIND        3..15
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFM12076.1"
FT   NON_TER         180
FT                   /evidence="ECO:0000313|EMBL:KFM12076.1"
SQ   SEQUENCE   180 AA;  19685 MW;  4E6A1C361EBB24C2 CRC64;
     QVWFKNRRAK WRKRERNQQM DLCKNGYVPQ FSGLMQPYDD MYAGYPYNNW ATKSLTPAPL
     STKSFTFFNS MSPLSSQSMF SAPSSISSMN MPSSMGHSAV PGMGNSGLNN INNISGSSLN
     SAMSSPACPY GPPGSPYSVY RDTCNSSLAS LRLKSKQHSS FGYSSLQSPG SSLNACQYNS
//